1. 靶点主信息
| NCBI Gene id: | 9971 |
| Gene_name: | NR1H4 |
| Gene alias: | BAR; FXR; HRR-1; HRR1; PFIC5; RIP14 |
| Map location: | 12q23.1 |
| Type of gene: | protein-coding |
| Description: | nuclear receptor subfamily 1 group H member 4 |
| OMIM_id: | 603826 |
| HGNC_id: | 7967 |
| Ensembl_id: | ENSG00000012504 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 艾叶 | leaf of Argy Wormwood | Folium Artemisiae Argyi |
| 霸王鞭 | Royle Euphorbia Latex | Euphorbia royleana |
| 白扁豆 | White Hyacinth Bean | Semen Lablab Album |
| 百部 | Root of Japanese Stemo | Radix Stemoe |
| 白鹅膏 | Goose Fat | Anser cygnoides domestica |
| 白饭豆 | Kidney Bean | Phaseolus vulgaris |
| 白附子 | rhizome of Giant Typhonium | Rhizoma Typhonii |
| 白果 | Ginkgo seed | Semen Ginkgo |
| 百合 | Bulb of Greenish Lily | Bulbus Lilii |
| 白花蛇舌草 | all - grass of Spreading Hedyotis | Herba Hedyotis Diffusae |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 474-25-9 | 鹅去氧胆酸 | Chenodiol | 10133 |
| 989-51-5 | 表没食子儿茶素没食子酸酯 | Epigallocatechin Gallate | 65064 |
| 83-48-7 | 豆甾醇 | Stigmasterol | 5280794 |
| 481-53-8 | 橘皮素 | Tangeretin | 68077 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acne Vulgaris | disease | 22763784 |
| Alzheimer's Disease | disease | 22300765 |
| Anti-Glomerular Basement Membrane Disease | disease | 21544063 |
| Arthritis, Experimental | disease | 26473505 |
| Blood Pressure | phenotype | 23103594 |
| Brain Edema | phenotype | 25582287 |
| Brain Neoplasms | group | 21257259 |
| Cachexia | phenotype | 21397390 |
| Carcinoma, Lewis Lung | disease | 21397390 |
| Cardiac Hypertrophy | phenotype | 26845648 |
