科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 制半夏
英文名称: Prepared tuber of Pinellia
拉丁名称: Rhizoma Pinelliae Preparata
使用部位: Pinellia ternata (Thunb.) Breit.
功用: Treatment of cough and asthma with much phlegm, dizziness and palpitation due to retention of phlegm and fluid, vertigo caused by wind-phlegm, headache with cold extremities due to attack of phlegm , stuffiness in the chest and the epigastrium, globus hystericus. Rhizoma Pineliae (processed with ginger) is often used for relieving nausea and vomiting. Rhizoma pinelliae (Proccessed with alum) for removing damp and phlegm. Rhizoma Pinelliae (unproccessed) is used externally for boils, sores and lymphadenitis.
适用症: Treatment of cough and asthma with much phlegm, dizziness and palpitation due to retention of phlegm and fluid, vertigo caused by wind-phlegm, headache with cold extremities due to attack of phlegm , stuffiness in the chest and the epigastrium, globus hys
毒副作用: Extremely Toxic

2. 相关成分

CAS号 中文名称 英文名称 参考文献
3775-73-3 (R)-3-氨基丁酸 (R)-3-Aminobutanoic Acid 5706670
473-98-3 白桦脂醇 Betulin 72326
472-15-1 白桦脂酸 Betulinic Acid 64971
55466-05-2 - JujubosideB 45358134

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
AXL ARK; JTK11; Tyro7; UFO 19q13.2 30128052
IL1B IL-1; IL1-BETA; IL1F2; IL1beta 2q14.1 28027595
IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 7p15.3 28027595
PRKAA1 AMPK; AMPKa1 5p13.1 26776965
PRKAA2 AMPK; AMPK2; AMPKa2; PRKAA 1p32.2 26776965
PRKAB1 AMPK; HAMPKb 12q24.23 26776965
SIRT1 SIR2; SIR2L1; SIR2alpha 10q21.3 26776965
SREBF1 SREBP1; bHLHd1 17p11.2 26776965
STK11 LKB1; PJS; hLKB1 19p13.3 26776965
TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F 6p21.33 28027595

4. 相关疾病

疾病名称 疾病类型 参考文献
Carcinogenesis phenotype 28027595
Inflammation phenotype 28027595
Liver neoplasms group 28027595
Neoplasms, Experimental phenotype 28027595
Obesity disease 28027595