1. 药材主信息
| 中文名称: | 云南甘草 |
| 英文名称: | Yunnan Licorice |
| 拉丁名称: | Glycyrrhiza yunnanensis |
| 使用部位: | root and rhizome |
| 功用: | See Glycyrrhiza uralensis . |
| 适用症: | See Glycyrrhiza uralensis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 20528-70-5 | - | (2S,3R,4aS,6aS,6bR,9S,10S,12aR,14bR)-3,10-dihydroxy-9-(hydroxymethyl)-2,4a,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-2-carboxylic acid | 131752021 |
| 2196-14-7 | 7,4'-二羟基黄酮 | 4',7-Dihydroxyflavone | 5282073 |
| 32272-23-4 | - | 4'-Hydroxy-7-methoxyflavone | 676307 |
| 471-53-4 | - | beta-Glycyrrhetic acid | 18526330 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 65242-64-0 | - | Glyzaglabrin | 5317777 |
| 5041-81-6 | 异甘草苷 | Isoliquiritin | 5318591 |
| 39022-00-9 | 3β,21α-Dihydroxyoleana-11,13(18)-dien-29-oic acid | Macedonic acid | 193076 |
| 6987-78-6 | - | Olean-12-en-28-oic acid, 3,21-dihydroxy-, gamma-lactone, (3beta,21beta)- | 21594250 |
| 961-29-5 | 异甘草素 | Trihydroxychalcone | 638278 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31438982 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 28933787 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 28933787 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 28933787 |
| CTTN | EMS1 | 11q13.3 | 30285892 |
| ERN1 | IRE1; IRE1P; IRE1a; hIRE1p | 17q23.3 | 28933787 |
| FGF2 | BFGF; FGF-2; FGFB; HBGF-2 | 4q28.1 | 31438982 |
| HRAS | C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; RASH1; p21ras | 11p15.5 | 30976491 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 28610608 |
| KRAS | C-K-RAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras; K-Ras 2; KI-RAS; KRAS1; KRAS2; NS; NS3; OES; RALD; RASK2; c-Ki-ras; c-Ki-ras2 | 12p12.1 | 30976491 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Cerebral Hemorrhage | phenotype | 28610608 |
| Corneal Neovascularization | disease | 31438982 |
| Glioma | disease | 31438982 |
| Lung Neoplasms | group | 30285892 |
| melanoma | disease | 30081934 |
| Sarcoma | group | 28933787 |
