1. 药材主信息
| 中文名称: | 罂粟壳 |
| 英文名称: | poppy capsule |
| 拉丁名称: | pericarpium papaveris |
| 使用部位: | capsule |
| 功用: | 1. Astringe the intestine, relieve diarrhea and alleviate pain. 2. Astringe the lung and relieve cough. |
| 适用症: | Enduring cough, chronic diarrhea, prolapse of rectum, pain in stomach duct and abdomen. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 5140-39-6 | - | (5bR,12bS,14S)-5b,6,7,8,12b,14-Hexahydro-10,11,14-trimethoxy-1,3-dioxolo(7,8)(2)benzopyrano(3,4-a)(3)benzazepine | 12309624 |
| 18694-10-5 | - | 5-[(6,7-Dimethoxyisoquinolin-1-yl)methyl]-2-methoxyphenol | 167736 |
| 73030-71-4 | 白术内酯III | Atractylenolide III | 155948 |
| 73030-71-4 | 白术内酯III | Atractylenolide III | 155948 |
| 76-57-3 | - | Codeine | 5284371 |
| 482-74-6 | - | Cryptopine | 72616 |
| 10504-35-5 | - | D-ascorbic acid | 54690394 |
| 530-26-7 | D-甘露糖 | D-Mannose | 18950 |
| 3606-45-9 | 二氢血根碱 | Dihydrosanguinarine | 124069 |
| 149-32-6 | 赤藓糖醇（赤藻糖醇） | Erythritol | 222285 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27154977 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31819036 |
| ASAH1 | AC; ACDase; ASAH; PHP; PHP32; SMAPME | 8p22 | 30735839 |
| ATG5 | APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 | 6q21 | 26472194 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 31163195 |
| CCND1 | BCL1; D11S287E; PRAD1; U21B31 | 11q13.3 | 31163195 |
| EIF4A1 | DDX2A; EIF-4A; EIF4A; eIF-4A-I; eIF4A-I | 17p13.1 | 31402318 |
| GSK3B | - | 3q13.33 | 27154977 |
| HIF1A | HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 | 14q23.2 | 31819036 |
| IFNG | IFG; IFI | 12q15 | 28240768 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Neoplasms | group | 26472194 |
| Edema | phenotype | 28240768 |
| Glioma | disease | 26472194 |
| Inflammation | phenotype | 28240768 |
| leukemia | disease | 27154977 |
| Liver neoplasms | group | 31163195 |
| Prostatic Neoplasms | group | 30735839 |
| Smoking | phenotype | 21903934 |
