1. 药材主信息
| 中文名称: | 野梧桐 |
| 英文名称: | Japanese Mallotus |
| 拉丁名称: | Mallotus japonicus |
| 使用部位: | bark |
| 功用: | To clear heat and resolve toxin, promote contraction and stanch bleeding. |
| 适用症: | Gastric ulcer, duodenal ulcer, hepatitis, hematuria, vaginal discharge, sores, bleeding due to external injury. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 477-90-7 | 岩白菜素 | Bergenin | 66065 |
| 14317-17-0 | - | Buxamine E | 442970 |
| 106-24-1 | 香叶醇 | Geraniol | 637566 |
| 116964-16-0 | - | Isobutyrylmallotochromene | 189453 |
| 98569-62-1 | - | Mallotochromene | 126969 |
| 86828-07-1 | - | Mallotojaponin | 122659 |
| 98569-63-2 | - | Mallotophenone | 179090 |
| 141-82-2 | 丙二酸 | Malonic acid | 867 |
| 120-73-0 | 嘌呤 | Purine | 1044 |
| 153-18-4 | 芦丁 | Rutin | 5280805 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 25281414 |
| IFNG | IFG; IFI | 12q15 | 25281414 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 25281414 |
| MPO | - | 17q22 | 25281414 |
| PPARGC1A | LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1 | 4p15.2 | 28049156 |
| S100A8 | 60B8AG; CAGA; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; P8 | 1q21.3 | 25281414 |
| SIRT1 | SIR2; SIR2L1; SIR2alpha | 10q21.3 | 28049156 |
| STAT4 | SLEB11 | 2q32.2-q32.3 | 25281414 |
| TFAM | MTDPS15; MTTF1; MTTFA; TCF6; TCF6L1; TCF6L2; TCF6L3 | 10q21.1 | 28049156 |
| TNF | DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F | 6p21.33 | 25281414 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Obesity | disease | 28049156 |
| Ventricular Remodeling | phenotype | 26185015 |
