1. 药材主信息
| 中文名称: | 希莶 |
| 英文名称: | Common St Paulswort Equivalent plant: Siegesbeckia |
| 拉丁名称: | Siegesbeckia orientalis |
| 使用部位: | aerial parts |
| 功用: | To dispel wind-damp, free channels and network vessels, clear heat and resolve toxin. |
| 适用症: | Wind-damp impediment pain, lassitude in lumbus and knees, hemiplegia, hypertension, malaria, jaundice, swelling toxin of welling abscess and sore, wind papules, damp sore, animal and insect bites. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 480-10-4 | 紫云英苷 | Astragalin | 5282102 |
| 27876-94-4 | 西红花酸；番红花酸;藏红花酸 | Crocetin | 5281232 |
| 5892-54-6 | Dimethylcrocetin | Crocetin dimethyl ester | 5316132 |
| 42553-65-1 | 西红花苷I | Crocin | 5281233 |
| 5940-00-1 | 豨莶精醇 | Darutigenol | 3037565 |
| 59219-65-7 | 豨莶苷 | Darutoside | 44715524 |
| 1080-67-7 | - | Epsilon-Cadinene | 12302130 |
| 439-89-4 | 龙胆碱 | Gentianine | 354616 |
| 853267-91-1 | Hythiemoside A | Hythiemoside A | 44607102 |
| 853267-90-0 | Hythiemoside B | Hythiemoside B | 11203296 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| NR1H2 | LXR-b; LXRB; NER; NER-I; RIP15; UNR | 19q13.33 | 24107776 |
| NR1H3 | LXR-a; LXRA; RLD-1 | 11p11.2 | 24107776 |
| NR1H4 | BAR; FXR; HRR-1; HRR1; PFIC5; RIP14 | 12q23.1 | 24107776 |
| TLR4 | ARMD10; CD284; TLR-4; TOLL | 9q33.1 | 24107776 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Liver diseases | group | 24107776 |
| Myopia | disease | 31394821 |
