科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 土茯苓
英文名称: Glabrous Greenbrier Rhizome
拉丁名称: Rhizoma Smilacis Glabrae
使用部位: rhizome
功用: To remove damp, to counteract toxicity, and to improve the mobility of joints.
适用症: Damp-heat with strangury turbidity, vaginal discharge, swollen welling abscess, scrofula, scab and lichen, syphilis, mercurial poisoning.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
483-76-1 (+)-DELTA-CADINENE - 441005
17283-81-7 Dihydro-Beta-Ionone - 519382
3646-73-9 α-D-Galactose - 439357
2438-10-0 (+)-萜品-4-醇 (+)-Terpinen-4-ol 2724161
111003-33-9 - (-)-Taxifolin 712316
480-41-1 - (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one 667495
502-73-8 16-三十一酮 16-Hentriacontanone 94741
2363-88-4 反式-2,4-癸二烯醛 2,4-Decadienal 5283349
104486-98-8 (+/-)-二氢山奈酚 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one 662
180981-12-8 - 3-Caffeoylshikimic acid 10131826

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCB1 ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 7q21.12 22011009
ABCB11 ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP 2q31.1 24107776
Abcb1b Abcb1; Mdr1; Mdr1b; Pgy-1; Pgy1; mdr 5 A1|5 3.43 cM 22011009
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 24107776
ABCG5 STSL; STSL2 2p21 24107776
ABCG8 GBD4; STSL; STSL1 2p21 24107776
ABL1 ABL; BCR-ABL; CHDSKM; JTK7; bcr/abl; c-ABL; c-ABL1; p150; v-abl 9q34.12 28796245
ACADM ACAD1; MCAD; MCADH 1p31.1 24146112
ACE2 ACEH Xp22.2 28935757
ACTA2 ACTSA 10q23.31 26891034

4. 相关疾病

疾病名称 疾病类型 参考文献
Acute kidney injury disease 26348276
Acute kidney injury disease 21975863
Acute Lung Injury disease 25512625
Adenoma group 26223300
Adenomatous Polyposis Coli disease 24516128
Adrenoleukodystrophy disease 25822341
Aging phenotype 25677910
Aging phenotype 28677234
Aging phenotype 28070015
Aging phenotype 23293221