1. 药材主信息
| 中文名称: | 铁子 |
| 英文名称: | African Myrsine |
| 拉丁名称: | Myrsine africana |
| 使用部位: | root or herb |
| 功用: | To dispel wind and relieve pain, clear heat and disinhibit damp, promote contraction and stanch bleeding. |
| 适用症: | Wind-damp impediment pain, toothache, diarrhea, dysentery, flooding, hematochezia, tuberculosis and hemoptysis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 58322-78-4 | - | 2-Hydroxychrysophanol | 442759 |
| 550-24-3 | 恩贝酸 | Embelin | 3218 |
| 518-82-1 | 大黄素 | Emodin | 3220 |
| 491-60-1 | 大黄素蒽酮 | Emodin anthrone | 122635 |
| 465-95-2 | 报春花皂苷元 | Primulagenin A | 10004345 |
| 65312-86-9 | 报春花皂苷I | Primulasaponin | 49787015 |
| 488-73-3 | 原栎醇 | Quercitol | 441437 |
| 488-73-3 | 原栎醇 | Quercitol | 441437 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| ARG1 | - | 6q23.2 | 30377563 |
| ASRGL1 | ALP; ALP1; CRASH | 11q12.3 | 25832436 |
| ATHS | ALP | 19p13.3-p13.2 | 25832436 |
| ATRNL1 | ALP; bA338L11.1; bA454H24.1 | 10q25.3 | 25832436 |
| BGLAP | BGP; OC; OCN | 1q22 | 25832436 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21565443 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21709246 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Ischemia | disease | 21709246 |
| Carcinoma | group | 25974735 |
| Carcinoma, Papillary | disease | 25974735 |
| Charcot-Marie-Tooth Disease | disease | 31695036 |
| Head and Neck Neoplasms | group | 24157255 |
| Inflammation | phenotype | 25128650 |
| Liver neoplasms | group | 23848338 |
| Multiple Myeloma | disease | 21565443 |
| Nasopharyngeal carcinoma | disease | 31731581 |
| Osteoporosis | disease | 25832436 |
