1. 药材主信息
| 中文名称: | 天山大黄 |
| 英文名称: | Tianshan Mountain Rhubarb |
| 拉丁名称: | Rheum wittrocki |
| 使用部位: | - |
| 功用: | - |
| 适用症: | - |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 21553-46-8 | 3,5-二甲基-4-甲氧基苯甲酸 | 3,5-Dimethyl-4-methoxybenzoic acid | 88944 |
| 38412-47-4 | 2,5-二甲基-7-羟基色酮 | 7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one | 5316891 |
| 4839-60-5 | 大黄酚-1-O-葡萄糖苷 | Chrysophanein | 6324923 |
| 481-74-3 | 大黄酚 | Chrysophanic acid | 10208 |
| 30197-14-9 | 去氧土大黄苷 | Desoxyrhaponticin | 5316606 |
| 499-20-7 | 蜀黍苷 | Dhurrin | 161355 |
| 518-82-1 | 大黄素 | Emodin | 3220 |
| 491-60-1 | 大黄素蒽酮 | Emodin anthrone | 122635 |
| 26296-54-8 | 大黄素甲醚-1-O-β-D-葡萄糖苷 | Physcion 8-glucoside | 5319323 |
| 27208-80-6 | 虎杖苷 | Polydatin | 5281718 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | 7q21.12 | 22011009 |
| Abcb1b | Abcb1; Mdr1; Mdr1b; Pgy-1; Pgy1; mdr | 5 A1|5 3.43 cM | 22011009 |
| ACE2 | ACEH | Xp22.2 | 28935757 |
| ACTA2 | ACTSA | 10q23.31 | 26891034 |
| ACTG2 | ACT; ACTA3; ACTE; ACTL3; ACTSG; VSCM | 2p13.1 | 23262250 |
| ADIPOQ | ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28 | 3q27.3 | 22388319 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 29566148 |
| AHR | RP85; bHLHe76 | 7p21.1 | 24247421 |
| AHR | RP85; bHLHe76 | 7p21.1 | 31027257 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 21975863 |
| Acute Lung Injury | disease | 25512625 |
| Adenoma | group | 26223300 |
| Adenomatous Polyposis Coli | disease | 24516128 |
| Adrenoleukodystrophy | disease | 25822341 |
| Aging | phenotype | 25677910 |
| Aging | phenotype | 28677234 |
| Aging | phenotype | 28070015 |
| Aging | phenotype | 23293221 |
| Aging | phenotype | 22304913 |
