1. 药材主信息
| 中文名称: | 天门冬 |
| 英文名称: | Cochinchinese Asparagus |
| 拉丁名称: | Asparagus cochinchinensis [Syn. Asparagus lucidus |
| 使用部位: | tuberoid |
| 功用: | To enrich yin and moisten dryness, clear lung and downbear fire. |
| 适用症: | Yin vacuity fever, cough with blood ejection, lung wilting, pulmonary welling abscess, swelling pain in throat, diabetes mellitus, constipation. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 96895-25-9 | nyasol | (-)-Nyasol | 6915833 |
| 185020-38-6 | (+)-Nyasol | 4-[(1Z,3S)-3-(4-hydroxyphenyl)penta-1,4-dienyl]phenol | 5281830 |
| 1917-64-2 | 5-甲氧基甲基-2-呋喃甲醛 | 5-(Methoxymethyl)-2-furaldehyde | 74711 |
| 67-47-0 | 5-羟甲基糠醛 | 5-Hydroxymethylfurfural | 237332 |
| 19725-44-1 | - | 7-Methoxy-2-methyl-3-phenyl-4H-chromen-4-one | 354368 |
| 70-47-3 | L-天冬酰胺 | Asparagine | 6267 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 32811-40-8 | 松柏醇 | Coniferyl Alcohol | 1549095 |
| 19057-60-4 | 薯蓣皂苷 | Dioscin | 119245 |
| 19083-00-2 | 纤细薯蓣皂苷 | Gracillin | 159861 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| ABL1 | ABL; BCR-ABL; CHDSKM; JTK7; bcr/abl; c-ABL; c-ABL1; p150; v-abl | 9q34.12 | 28796245 |
| ACADM | ACAD1; MCAD; MCADH | 1p31.1 | 24146112 |
| AHSA1 | AHA1; C14orf3; hAha1; p38 | 14q24.3 | 29158824 |
| AIMP2 | HLD17; JTV-1; JTV1; P38 | 7p22.1 | 29158824 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 23552851 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27155058 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 26348276 |
| Bone neoplasms | group | 29497056 |
| Cardiotoxicity | disease | 29524841 |
| Fatty Liver, Alcoholic | disease | 24146112 |
| Infarction, Middle Cerebral Artery | disease | 25772012 |
| Ischemic stroke | disease | 25772012 |
| Kidney Diseases | group | 27431331 |
| Liver diseases | group | 24107776 |
| Liver neoplasms | group | 30710454 |
| Lung Neoplasms | group | 23552851 |
