科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 胜红蓟
英文名称: Tropic Ageratum
拉丁名称: Ageratum conyzoides
使用部位: whole herb
功用: To clear heat and resolve toxin, stanch bleeding, relieve pain.
适用症: Common cold with fever, swelling pain in throat, hemoptysis, spontaneous external bleeding, flooding and spotting, pain in stomach duct and abdomen, wind-damp impediment pain, knocks and falls, bleeding due to external injury, swelling toxin of welling abscess and sore, eczema titillation.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
18794-84-8 反式-β-金合欢烯 - 5281517
17430-12-5 - (3R,6E)-nerolidol 11241545
18022-66-7 3,4-二甲基-3-环己烯甲醛 3,4-Dimethyl-3-cyclohexenylmethanal 537551
7541-49-3 叶绿醇 3,7,11,15-Tetramethyl-2-hexadecen-1-OL 5366244
29043-07-0 5,7,3',4',5'-五甲氧基黄酮 5,6,7,3',4',5'-Hexamethoxyflavone 185670
74-79-3 L-精氨酸 Arginine 6322
1783-96-6 D-天冬氨酸 D-Aspartic acid 83887
349-46-2 D-胱氨酸 D-Cystine 6857538
348-67-4 D-甲硫氨酸 D-Methionine 84815
56-40-6 甘氨酸 Glycine 750

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCB11 ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP 2q31.1 24107776
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 24107776
ABCG5 STSL; STSL2 2p21 24107776
ABCG8 GBD4; STSL; STSL1 2p21 24107776
APP AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 21q21.3 24107941
BACE1 ASP2; BACE; HSPC104 11q23.3 24107941
CNR2 CB-2; CB2; CX5 1p36.11 31883107
NR1H2 LXR-b; LXRB; NER; NER-I; RIP15; UNR 19q13.33 24107776
NR1H3 LXR-a; LXRA; RLD-1 11p11.2 24107776
NR1H4 BAR; FXR; HRR-1; HRR1; PFIC5; RIP14 12q23.1 24107776

4. 相关疾病

疾病名称 疾病类型 参考文献
Liver diseases group 24107776