1. 药材主信息
| 中文名称: | 牛心番荔枝 |
| 英文名称: | Bullocksheart Custardapple |
| 拉丁名称: | Annona reticulata |
| 使用部位: | fruit |
| 功用: | To clear heat and check dysentery, expel worms. |
| 适用症: | Heat toxin dysentery, intestinal parasitic disease. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 1862-41-5 | - | Anonaine | 160597 |
| 121-54-0 | 苄索氯铵 | Benzethonium Chloride | 8478 |
| 475-75-2 | 鹅掌楸碱 | Liriodenine | 10144 |
| 129683-96-1 | - | Murisolin | 11399084 |
| 485-19-8 | 牛心果碱；瑞枯灵 | Reticuline | 439653 |
| 485-19-8 | 牛心果碱；瑞枯灵 | Reticuline | 439653 |
| 96574-01-5 | 丹酚酸A | Salvianolic acid A | 5281793 |
| 123123-32-0 | - | Squamocin G | 183613 |
| 517-71-5 | Xylopine | Xylopine | 160503 |
| 523-02-4 | - | Xylopinine | 226520 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24486344 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31193821 |
| ALOX5 | 5-LO; 5-LOX; 5LPG; LOG5 | 10q11.21 | 24033467 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 27609227 |
| BCL2L11 | BAM; BIM; BOD | 2q13 | 31193821 |
| BDNF | ANON2; BULN2 | 11p14.1 | 27609227 |
| CDK5 | LIS7; PSSALRE | 7q36.1 | 27609227 |
| CDK5R1 | CDK5P35; CDK5R; NCK5A; p23; p25; p35; p35nck5a | 17q11.2 | 27609227 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 27609227 |
| DCX | DBCN; DC; LISX; SCLH; XLIS | Xq23 | 27609227 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Ischemia | disease | 27609227 |
| Cerebral Ischemia | disease | 31193821 |
| Inflammation | phenotype | 24033467 |
| Macular degeneration | disease | 24486344 |
| Myocardial Ischemia | disease | 30361065 |
| Pneumonia | disease | 31969071 |
| Reperfusion Injury | disease | 31193821 |
| Reperfusion Injury | disease | 27609227 |
