1. 药材主信息
| 中文名称: | 牛西西 |
| 英文名称: | Patience Dock |
| 拉丁名称: | Rumex patientia |
| 使用部位: | root |
| 功用: | To clear heat and resolve toxin, stanch bleeding and disperse swelling, free stool and kill worms. |
| 适用症: | Blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, red and white vaginal discharge, purpura, dysentery, hepatitis, constipation, inhibited urination, swelling toxin of welling abscess and sore, scab and lichen, knocks and falls, burns and scalds. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 481-72-1 | 芦荟大黄素 | Aloe emodin | 10207 |
| 481-74-3 | 大黄酚 | Chrysophanic acid | 10208 |
| 154-23-4 | (+)-儿茶素 | Cianidanol | 9064 |
| 518-82-1 | 大黄素 | Emodin | 3220 |
| 3785-24-8 | 酸模素 | Nepodin | 100780 |
| 504-15-4 | 苔黑酚 | Orcinol | 10436 |
| 84268-38-2 | - | Physcion 8-gentiobioside | 442762 |
| 521-61-9 | 大黄素甲醚 | Physcione | 10639 |
| 13241-28-6 | 大黄酚-8-O-葡萄糖苷 | Pulmatin | 442731 |
| 3774-64-9 | 1,6-二羟基-8-甲氧基-3-甲基蒽-9,10-二酮 | Questin | 160717 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24125861 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24359639 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25050737 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| ASRGL1 | ALP; ALP1; CRASH | 11q12.3 | 25832436 |
| ATG12 | APG12; APG12L; FBR93; HAPG12 | 5q22.3 | 24359639 |
| ATG5 | APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 | 6q21 | 24125861 |
| ATG7 | APG7-LIKE; APG7L; GSA7 | 3p25.3 | 24125861 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 25661734 |
| Asthma | disease | 23995289 |
| Colorectal Neoplasms | group | 28570591 |
| Head and Neck Neoplasms | group | 24157255 |
| Hyperpigmentation | phenotype | 31176710 |
| leukemia | disease | 27270429 |
| Liver neoplasms | group | 23848338 |
| Liver Neoplasms, Experimental | phenotype | 28570591 |
| melanoma | disease | 27343979 |
| Nasopharyngeal carcinoma | disease | 31731581 |
