1. 药材主信息
| 中文名称: | 绵毛马兜铃 |
| 英文名称: | Wooly Dutchmanspipe |
| 拉丁名称: | Aristolochia mollissima |
| 使用部位: | rhizome or whole herb |
| 功用: | To dispel wind and eliminate damp, quicken blood and free network vessels, relieve pain. |
| 适用症: | Wind-damp impediment pain, numbness in limbs, hypertonicity of sinews and bones, pain in stomach duct and abdomen, painful wound from knocks and falls, bleeding due to external injury, mammary welling abscess, suppurative infection. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 122739-09-7 | - | 9-Ethoxyaristololactam | 195368 |
| 97-59-6 | 尿囊素 | Allantoin | 204 |
| 53948-07-5 | Aristolactam AII | Aristolactam AII | 148657 |
| 97399-91-2 | 马兜铃内酰胺AIIIa | Aristolactam AIIIa | 10356352 |
| 313-67-7 | 马兜铃酸A | Aristolochic acid | 2236 |
| 1261395-75-8 | 马兜铃酸D | Aristolochic acid d | 161218 |
| 475-80-9 | 马兜铃酸B | Aristolochic acid II | 108168 |
| 13395-02-3 | 马兜铃内酰胺I | Aristololactam | 96710 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 55610-01-0 | Cepharadione A | Cepharadione A | 94577 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| NR1H2 | LXR-b; LXRB; NER; NER-I; RIP15; UNR | 19q13.33 | 24107776 |
| NR1H3 | LXR-a; LXRA; RLD-1 | 11p11.2 | 24107776 |
| NR1H4 | BAR; FXR; HRR-1; HRR1; PFIC5; RIP14 | 12q23.1 | 24107776 |
| TLR4 | ARMD10; CD284; TLR-4; TOLL | 9q33.1 | 24107776 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Liver diseases | group | 24107776 |
| Pain | phenotype | 28396565 |
