1. 药材主信息
| 中文名称: | 路边青 |
| 英文名称: | Manyflower Glorybower Leaf |
| 拉丁名称: | Clerodendron cyrtophyllum |
| 使用部位: | stem-leaf |
| 功用: | To clear heat and resolve toxin, cool blood and stanch bleeding. |
| 适用症: | Febrile diseases due to external contraction, exuberant heat and vexation thirst, swelling pain in throat, mouth sore, jaundice, heat toxin dysentery, acute enteritis, swelling toxin of welling abscess and flat abscess, spontaneous external bleeding, blood strangury, bleeding due to external injury. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 916347-31-4 | 断血流皂苷A | 2-[[4,5-Dihydroxy-6-[[8-hydroxy-5,8a-bis(hydroxymethyl)-5,6a,6b,11,11,14b-hexamethyl-1,2,3,4,4a,6,7,8,9,10,12,14a-dodecahydropicen-3-yl]oxy]-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol | 71571492 |
| 67-47-0 | 5-羟甲基糠醛 | 5-Hydroxymethylfurfural | 237332 |
| 480-10-4 | 紫云英苷 | Astragalin | 5282102 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 331-39-5 | 咖啡酸 | Caffeic Acid | 689043 |
| 2364-23-0 | - | Clerosterol | 5283638 |
| 149-91-7 | 没食子酸 | Gallic Acid | 370 |
| 482-35-9 | 槲皮素-3-O-葡萄糖苷（异槲皮苷） | Isoquercetin | 5280804 |
| 520-18-3 | 山柰素（山柰酚） | Kaempferol | 5280863 |
| 56-88-2 | L-胱硫醚 | L-cystathionine | 439258 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| ATF4 | CREB-2; CREB2; TAXREB67; TXREB | 22q13.1 | 26661339 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 30447302 |
| Cognition Disorders | group | 21708244 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Inflammation | phenotype | 21708244 |
| leukemia | disease | 23584398 |
| leukemia | disease | 21950524 |
| Liver Cirrhosis, Experimental | disease | 21168456 |
| Liver diseases | group | 24107776 |
