1. 药材主信息
| 中文名称: | 两面针 |
| 英文名称: | Shinyleaf Pricklyash Root |
| 拉丁名称: | Radix Zanthoxyli |
| 使用部位: | - |
| 功用: | To promote the flow of qi, relieve pain, to eliminate blood stasis, to promote blood circulation and dispel wind. |
| 适用症: | Treatment of traumatic injury, rheumatic arthralgia, stomach-ache, teethache, bitten by venomous snake, applied for burn caused by hot liquid or fire. |
| 毒副作用: | Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 530-55-2 | 2,6-二甲基-1,4-苯醌 | 2,6-Dimethoxyquinone | 68262 |
| 99-96-7 | 对羟基苯甲酸 | 4-Hydroxybenzoic acid | 135 |
| 99-96-7 | 对羟基苯甲酸 | 4-Hydroxybenzoic acid | 135 |
| 55085-47-7 | 5,6,7-三甲氧基香豆素 | 5,6,7-Trimethoxycoumarin | 148724 |
| 60796-65-8 | 5,7,8-TRIMETHOXYCOUMARIN | 5,7,8-Trimethoxycoumarin | 6482974 |
| 24240-04-8 | 别隐品碱 | Allocryptopine | 98570 |
| 60394-88-9 | - | Arnottianamide | 3085181 |
| 133-05-1 | 细辛脂素 | Asarinin | 101612 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30825187 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25047426 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27154977 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31819036 |
| ASAH1 | AC; ACDase; ASAH; PHP; PHP32; SMAPME | 8p22 | 30735839 |
| ATG5 | APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 | 6q21 | 26472194 |
| AURKA | AIK; ARK1; AURA; BTAK; PPP1R47; STK15; STK6; STK7 | 20q13.2 | 25047426 |
| BAX | BCL2L4 | 19q13.33 | 25047426 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 25047426 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 31163195 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute Lung Injury | disease | 26361726 |
| Brain Neoplasms | group | 26472194 |
| Carcinogenesis | phenotype | 25047426 |
| Colonic Neoplasms | group | 25047426 |
| Epilepsy | disease | 29925377 |
| Glioma | disease | 26472194 |
| Hypoxia-Ischemia, Brain | disease | 29925377 |
| Inflammation | phenotype | 26361726 |
| leukemia | disease | 27154977 |
| Liver neoplasms | group | 31163195 |
