1. 药材主信息
| 中文名称: | 款冬花 |
| 英文名称: | flower bud of common coltsfoot |
| 拉丁名称: | flos farfarae |
| 使用部位: | - |
| 功用: | To relieve cough and resolve phlegm to nourish the lung to keep the adverse qi downward. |
| 适用症: | Cough, cough and asthma with abundant phlegm, consumption cough and hemoptysis, chronic bronchitis, infection of upper respiratory tract, tuberculosis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 2243-33-6 | - | (+)-alpha-Phellandrene | 443160 |
| 136458-42-9 | - | (1aR,4aS,7R,7aR,7bR)-1,1,7-Trimethyl-4-methylidenedecahydro-1H-cyclopropa(e)azulen-7-ol | 178323 |
| 2318-18-5 | - | (1R,4Z,6S,7R,11Z)-4-ethylidene-7-hydroxy-6,7,14-trimethyl-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-3,8,17-trione | 102004936 |
| 97-67-6 | L-苹果酸 | (2S)-2-Hydroxybutanedioic acid | 222656 |
| 1730-91-2 | (S)-(+)-2-甲基丁酸 | (S)-2-methylbutanoic acid | 448893 |
| 21964-49-8 | (1,13-十四烷二)烯 | 1,13-Tetradecadiene | 30875 |
| 18483-17-5 | 1,3,6-三-O-没食子酰葡萄糖 | 1,3,6-tri-O-galloyl-beta-D-glucose | 452707 |
| 37309-58-3 | - | 1-Decene | 13381 |
| 37309-58-3 | - | 1-Decene | 13381 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| CHRNA7 | CHRNA7-2; NACHRA7 | 15q13.3 | 31560162 |
| CTBP1 | BARS; HADDTS | 4p16.3 | 29988033 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 25281414 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Aging | phenotype | 24932939 |
| Alzheimer's Disease | disease | 31560162 |
| Alzheimer's Disease | disease | 30447302 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes | disease | 28707095 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Down Syndrome | disease | 24932939 |
| Hyperglycemia | disease | 28707095 |
