1. 药材主信息
| 中文名称: | 苦檀子 |
| 英文名称: | Thickfruit Millettia |
| 拉丁名称: | Millettia pachycarpa |
| 使用部位: | seed or fruit |
| 功用: | To attack toxin and relieve pain, disperse accumulation and kill worms. |
| 适用症: | Scab and lichen, sore lai, sand qi abdominal pain, child gan accumulation. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 492-08-0 | 鹰爪豆碱(液体) | (+)-Sparteine | 7014 |
| 51225-28-6 | 6,8-二异戊烯基金雀异黄素 | 6,8-Diprenylgenistein | 480783 |
| 76754-24-0 | Lupalbigenin | Lupalbigenin | 10001388 |
| 83-79-4 | 鱼藤酮 | Rotenone | 6758 |
| 82-08-6 | Rottlerin | Rottlerin | 5281847 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24125861 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24359639 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25050737 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 22229260 |
| ATG12 | APG12; APG12L; FBR93; HAPG12 | 5q22.3 | 24359639 |
| ATG5 | APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 | 6q21 | 24125861 |
| ATG7 | APG7-LIKE; APG7L; GSA7 | 3p25.3 | 24125861 |
| BAX | BCL2L4 | 19q13.33 | 25050737 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 24359639 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 25050737 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 25661734 |
| Alzheimer's Disease | disease | 22229260 |
| Asthma | disease | 23995289 |
| Colorectal Neoplasms | group | 28570591 |
| Demyelinating Diseases | group | 23816754 |
| Hyperalgesia | phenotype | 22244441 |
| Hyperpigmentation | phenotype | 31176710 |
| Liver Neoplasms, Experimental | phenotype | 28570591 |
| Lung Neoplasms | group | 25522273 |
| melanoma | disease | 27343979 |
