1. 药材主信息
| 中文名称: | 蓟罂粟 |
| 英文名称: | Mexican Pricklepoppy |
| 拉丁名称: | Argemone mexicana |
| 使用部位: | whole herb |
| 功用: | To effuse sweat and disinhibit water, clear heat and resolve toxin, relieve pain and itch. |
| 适用症: | Common cold without sweating, jaundice, strangury, edema, eyelid laceration, mounting qi , scab and lai, syphilis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 6901-16-2 | - | (-)-Argemonine | 442168 |
| 104109-37-7 | 11(α)甲氧基柴胡皂苷F | 11(alpha)-methoxysaikosaponin F | 73818265 |
| 1486-70-0 | 3-邻甲基槲皮素 | 3-Methoxyluteolin | 5280681 |
| 24240-04-8 | 别隐品碱 | Allocryptopine | 98570 |
| 2086-83-1 | 小檗碱 | Berberine | 2353 |
| 478-03-5 | - | Chelerythrine hydroxide | 5351594 |
| 482-74-6 | - | Cryptopine | 72616 |
| 552-29-4 | - | Oxyhydrastinine | 160522 |
| 130-86-9 | 原阿片碱 | Protopine | 4970 |
| 2447-54-3 | 血根碱 | Sanguinarium | 5154 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27154977 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31819036 |
| ANXA5 | ANX5; ENX2; HEL-S-7; PP4; RPRGL3 | 4q27 | 25682924 |
| ASAH1 | AC; ACDase; ASAH; PHP; PHP32; SMAPME | 8p22 | 30735839 |
| ATG5 | APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 | 6q21 | 26472194 |
| BAX | BCL2L4 | 19q13.33 | 25682924 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22033245 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 31163195 |
| BECN1 | ATG6; VPS30; beclin1 | 17q21.31 | 28288416 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21496227 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Neoplasms | group | 26472194 |
| Carcinoma, Ovarian Epithelial | disease | 28990249 |
| Diabetes Mellitus, Experimental | disease | 27067643 |
| Diabetes Mellitus, Experimental | disease | 20304443 |
| Glioma | disease | 26472194 |
| Glucose tolerance test | phenotype | 20304443 |
| Hyperglycemia | disease | 27067643 |
| Insulin Resistance | phenotype | 22019891 |
| Insulin Resistance | phenotype | 20304443 |
| Left Ventricular Hypertrophy | disease | 31371114 |
