1. 药材主信息
| 中文名称: | 蒺藜 |
| 英文名称: | Puncturevine Caltrop Fruit |
| 拉丁名称: | Fructus Tribuli |
| 使用部位: | - |
| 功用: | To subdue hyperactivity of the liver, to promote blood circulation, to dispel wind, to clear the eye of opacity, and to arrest itching. |
| 适用症: | 1. Antitussive, expectorant and antiasthmatic. 2. Its alcoholic infusion exerts hypotensive effect in anesthetized animals. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 7785-53-7 | - | (+)-alpha-Terpineol | 442501 |
| 16620-96-5 | - | 6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline | 27694 |
| 244-63-3 | 9H-吡啶[3,4-b]吲哚 | 9H-Pyrido[3,4-B]indole | 64961 |
| 1862-41-5 | - | Anonaine | 160597 |
| 65-85-0 | 苯甲酸 | Benzoic Acid | 243 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 19057-60-4 | 薯蓣皂苷 | Dioscin | 119245 |
| 14144-06-0 | 地索苷; 延龄草苷 | Disogluside | 11827970 |
| 518-82-1 | 大黄素 | Emodin | 3220 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABL1 | ABL; BCR-ABL; CHDSKM; JTK7; bcr/abl; c-ABL; c-ABL1; p150; v-abl | 9q34.12 | 28796245 |
| ACADM | ACAD1; MCAD; MCADH | 1p31.1 | 24146112 |
| ADRB2 | ADRB2R; ADRBR; B2AR; BAR; BETA2AR | 5q32 | 26746354 |
| AHSA1 | AHA1; C14orf3; hAha1; p38 | 14q24.3 | 29158824 |
| AIMP2 | HLD17; JTV-1; JTV1; P38 | 7p22.1 | 29158824 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 23552851 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27155058 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 28095588 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29497056 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 26348276 |
| Blood Pressure | phenotype | 25076013 |
| Bone neoplasms | group | 29497056 |
| Brain Ischemia | disease | 30414381 |
| Brain Neoplasms | group | 30922391 |
| Cardiotoxicity | disease | 29524841 |
| Colorectal Neoplasms | group | 23824743 |
| Cystadenocarcinoma, Serous | disease | 29879497 |
| Diabetes | disease | 25751815 |
| Diabetes Mellitus, Experimental | disease | 30129056 |
