1. 药材主信息
| 中文名称: | 桦木皮 |
| 英文名称: | Asian White Birch Bark Equivalent plant: Betula pl |
| 拉丁名称: | Betula platyphylla var. japonica |
| 使用部位: | bark |
| 功用: | To clear heat and disinhibit damp, relieve cough and dispel phlegm, resolve toxin and disperse swelling. |
| 适用症: | Pneumonia, dysentery, diarrhea, jaundice, nephritis, urinary tract infection, chronic trachitis, acute tonsillitis, periodontitis, acute mastitis, swollen boil, itchy papules, scalds. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 473-98-3 | 白桦脂醇 | Betulin | 72326 |
| 552-41-0 | 丹皮酚 | Paeonol | 11092 |
| 257301-36-3 | Platyphyllonol | Platyphyllonol | 92448097 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31406198 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 28027595 |
| IL6 | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 | 7p15.3 | 28027595 |
| MTOR | FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS | 1p36.22 | 31406198 |
| PRKAA1 | AMPK; AMPKa1 | 5p13.1 | 26776965 |
| PRKAA2 | AMPK; AMPK2; AMPKa2; PRKAA | 1p32.2 | 26776965 |
| PRKAB1 | AMPK; HAMPKb | 12q24.23 | 26776965 |
| SIRT1 | SIR2; SIR2L1; SIR2alpha | 10q21.3 | 26776965 |
| SREBF1 | SREBP1; bHLHd1 | 17p11.2 | 26776965 |
| STK11 | LKB1; PJS; hLKB1 | 19p13.3 | 26776965 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinogenesis | phenotype | 28027595 |
| Inflammation | phenotype | 28027595 |
| Liver neoplasms | group | 28027595 |
| Neoplasms, Experimental | phenotype | 28027595 |
| Obesity | disease | 28027595 |
