科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 含羞草
英文名称: Sensitive Plant
拉丁名称: Mimosa pudica
使用部位: whole herb
功用: To cool blood and resolve toxin, clear heat and disinhibit damp, quiet spirit and calm.
适用症: Common cold, infant ardent fever, bronchitis, hepatitis, gastritis, enteritis, conjunctivitis, calculus of urinary system, edema, taxation damage hemoptysis, nosebleed(epistaxis), hematuria, neurasthenia, neurosis, insomnia, toxin swelling of sores, zoster, knocks and falls.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
2769-94-0 2,4-bis(1-phenylethyl)phenol 2,4-Bis(1-phenylethyl)phenol 102877
477-90-7 岩白菜素 Bergenin 66065
83-46-5 β-谷甾醇 Beta-Sitosterol 222284
331-39-5 咖啡酸 Caffeic Acid 689043
154-23-4 (+)-儿茶素 Cianidanol 9064
84-69-5 - Diisobutyl phthalate 6782
3195-01-5 Norarmepavine L-(-)-N-norarmepavine 6999736
500-44-7 含羞草素 Mimosine 440473
634-97-9 吡咯-2-甲酸 Pyrrole-2-carboxylic acid 12473
83-48-7 豆甾醇 Stigmasterol 5280794

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCB11 ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP 2q31.1 24107776
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 24107776
ABCG5 STSL; STSL2 2p21 24107776
ABCG8 GBD4; STSL; STSL1 2p21 24107776
APP AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 21q21.3 24107941
BACE1 ASP2; BACE; HSPC104 11q23.3 24107941
NR1H2 LXR-b; LXRB; NER; NER-I; RIP15; UNR 19q13.33 24107776
NR1H3 LXR-a; LXRA; RLD-1 11p11.2 24107776
NR1H4 BAR; FXR; HRR-1; HRR1; PFIC5; RIP14 12q23.1 24107776
TLR4 ARMD10; CD284; TLR-4; TOLL 9q33.1 24107776

4. 相关疾病

疾病名称 疾病类型 参考文献
Cardiomyopathies group 31064352
Liver diseases group 24107776