1. 药材主信息
| 中文名称: | 贯众 |
| 英文名称: | root of Chinese Angelica |
| 拉丁名称: | Rhizoma Dryopteris crassirhizomae |
| 使用部位: | - |
| 功用: | 1. To kill parasites; 2. To clear heat and release toxins; 3. To stop bleeding |
| 适用症: | Wind-heat common cold, warm heat macular eruption, blood ejection, hemoptysis, spontaneous external bleeding, hematochezia, flooding and spotting, blood dysentery, vaginal discharge, ancylostomiasis, ascariasis, oxyuria disease. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 550-79-8 | - | Afrormosin | 5281704 |
| 58409-52-2 | - | Albaspidin | 42738 |
| 3570-40-9 | 白绵马素AA | Albaspidin AA | 14378646 |
| 59092-91-0 | 白绵马素AP | Albaspidin AP | 25096734 |
| 584-28-1 | - | Aspidin | 120290 |
| 19489-48-6 | - | Aspidinin | 633694 |
| 519-40-4 | - | Aspidinol | 122841 |
| 20063-89-2 | DL-氮杂环丁烷-2-羧酸 | Azetidine-2-carboxylic acid | 17288 |
| 32884-36-9 | Cajanin | Cajanin | 5281706 |
| 1783-96-6 | D-天冬氨酸 | D-Aspartic acid | 83887 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCA1 | ABC-1; ABC1; CERP; HDLCQTL13; HDLDT1; HPALP1; TGD | 9q31.1 | 26558782 |
| ABCG1 | ABC8; WHITE1 | 21q22.3 | 26558782 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31438982 |
| APOE | AD2; APO-E; ApoE4; LDLCQ5; LPG | 19q13.32 | 26558782 |
| CTTN | EMS1 | 11q13.3 | 30285892 |
| EPHB2 | BDPLT22; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5 | 1p36.12 | 24631489 |
| FGF2 | BFGF; FGF-2; FGFB; HBGF-2 | 4q28.1 | 31438982 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 28610608 |
| LRIG1 | LIG-1; LIG1 | 3p14.1 | 30081934 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 22931352 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Asthma | disease | 31226782 |
| Body Weight | phenotype | 21557739 |
| Cerebral Hemorrhage | phenotype | 28610608 |
| Corneal Neovascularization | disease | 31438982 |
| Fatty Liver | disease | 21557739 |
| Glioma | disease | 31438982 |
| Hyperplasia | phenotype | 31226782 |
| Hypoxia | phenotype | 22743170 |
| Lung Neoplasms | group | 30285892 |
| melanoma | disease | 30081934 |
