1. 药材主信息
| 中文名称: | 福寿草? |
| 英文名称: | Amur Adonis |
| 拉丁名称: | Adonis amurensis |
| 使用部位: | whole herb |
| 功用: | To strengthen heart, disinhibit urine, calm. |
| 适用症: | Cardiac insufficiency, atrial fibrillation, congestive cardiac failure, edema due to heart disease, CNS depression. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 26708-71-4 | - | (3S,8R,9S,10R,17S)-17-acetyl-3-hydroxy-10-methyl-2,3,4,7,8,9,11,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-12-one | 101306708 |
| 6869-50-7 | - | 14beta,17alpha-Pregn-5-en-20-one, 3beta,8,12beta,14-tetrahydroxy- | 12311278 |
| 21637-25-2 | - | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one | 51402807 |
| 3253-62-1 | - | 3-[(3S,5S,8R,9S,10R,13R,14S,17R)-5,14-dihydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one | 101289682 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 508-75-8 | 铃兰毒苷 | Convallatoxin | 441852 |
| 508-76-9 | - | Corchorozide A | 56840797 |
| 143-62-4 | 毛地黄毒苷配基 | Digitoxigenin | 4369270 |
| 71-63-6 | - | Digitoxin | 441207 |
| 6029-87-4 | - | Isocromadurine | 442726 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 21445586 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 28688145 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21871133 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 21871133 |
| CASR | CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR | 3q13.33-q21.1 | 21445586 |
| CAT | - | 11p13 | 29179721 |
| CAT | - | 11p13 | 24559844 |
| CD274 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 | 9p24.1 | 27378243 |
| CDC37 | P50CDC37 | 19p13.2 | 21871133 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Blood Pressure | phenotype | 28143892 |
| Body Weight | phenotype | 24559844 |
| Epstein-Barr Virus Infections | group | 28056971 |
| Fibrosis | phenotype | 28143892 |
| Inflammation | phenotype | 27374313 |
| Liver Neoplasms, Experimental | phenotype | 21445586 |
| Lung Neoplasms | group | 21550230 |
| Lung Neoplasms | group | 28916653 |
| melanoma | disease | 27545456 |
