1. 药材主信息
| 中文名称: | 独活 |
| 英文名称: | Doubleteeth Pubescent Angelica Root |
| 拉丁名称: | Radix Angelicae Pubescentis |
| 使用部位: | root |
| 功用: | To relieve rheumatic conditions, and to remove obstruction from the channels and relieve pain. |
| 适用症: | Wind-cold-damp impediment (especially in lower part of body), pain in lumbus and knees, headache, toothache. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 13877-91-3 | 罗勒烯 | - | 5281553 |
| 495-61-4 | (-)-β-bisabolene | - | 10104370 |
| 99-83-2 | 水芹烯 | - | 7460 |
| 50894-66-1 | - | (+)-alpha-Funebrene | 6552024 |
| 2243-33-6 | - | (+)-alpha-Phellandrene | 443160 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 7785-53-7 | - | (+)-alpha-Terpineol | 442501 |
| 515-69-5 | - | (+)-Epi-alpha-bisabolol | 1201551 |
| 1461-27-4 | - | (+)-m-Mentha-1(6),8-diene | 12304570 |
| 20296-50-8 | - | (-)-3-Carene | 442461 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCA1 | ABC-1; ABC1; CERP; HDLCQTL13; HDLDT1; HPALP1; TGD | 9q31.1 | 26558782 |
| ABCG1 | ABC8; WHITE1 | 21q22.3 | 26558782 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| APOE | AD2; APO-E; ApoE4; LDLCQ5; LPG | 19q13.32 | 26558782 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 25790909 |
| CAT | - | 11p13 | 24559844 |
| CCNB1 | CCNB | 5q13.2 | 24763055 |
| CDK1 | CDC2; CDC28A; P34CDC2 | 10q21.2 | 24577085 |
| CDK1 | CDC2; CDC28A; P34CDC2 | 10q21.2 | 24763055 |
| CDK2 | CDKN2; p33(CDK2) | 12q13.2 | 25790909 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Allergic asthma | disease | 28782757 |
| Body Weight | phenotype | 24559844 |
| Body Weight | phenotype | 21557739 |
| Brain Edema | phenotype | 26337552 |
| Brain Neoplasms | group | 24577085 |
| Colorectal Neoplasms | group | 24763055 |
| Encephalitis | disease | 26337552 |
| Fatty Liver | disease | 21557739 |
| Hypoxia | phenotype | 22743170 |
| Inflammation | phenotype | 24858719 |
