1. 药材主信息
| 中文名称: | 滇紫草 |
| 英文名称: | Paniculate Onosma |
| 拉丁名称: | Onosma paniculatum |
| 使用部位: | root or root cortex |
| 功用: | To clear heat, resolve toxin, cool blood, quicken blood. |
| 适用症: | Measles papules, pneumonia, febrile diseases macular eruption, ulcerating sores, eczema, scalds. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 24502-79-2 | β,β-二甲基丙烯酰紫草素 | beta,beta-Dimethylacrylshikonin | 479499 |
| 7415-78-3 | - | Beta-Hydroxyisovalerylshikonin | 479502 |
| 517-89-5 | 紫草素（右旋） | Shikonin | 479503 |
| 94451-22-6 | - | Shinjulactone K | 460541 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 22011623 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24106286 |
| BAX | BCL2L4 | 19q13.33 | 25879420 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 25879420 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 26275605 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 25879420 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 26275605 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 25879420 |
| CCL4 | ACT2; AT744.1; G-26; HC21; LAG-1; LAG1; MIP-1-beta; MIP1B; MIP1B1; SCYA2; SCYA4 | 17q12 | 22494696 |
| CCL5 | D17S136E; RANTES; SCYA5; SIS-delta; SISd; TCP228; eoCP | 17q12 | 22494696 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute Lung Injury | disease | 29243243 |
| Cicatrix, Hypertrophic | disease | 26275605 |
| Colonic Neoplasms | group | 27556106 |
| Endotoxemia | phenotype | 25019241 |
| Glioma | disease | 31560934 |
| Glioma | disease | 29608987 |
| Glioma | disease | 28108311 |
| Inflammation | phenotype | 29243243 |
| leukemia | disease | 24583460 |
| Liver neoplasms | group | 22011623 |
