1. 药材主信息
| 中文名称: | 大叶蛇葡萄 |
| 英文名称: | Largeleaf Ampelopsis |
| 拉丁名称: | Ampelopsis megalophylla |
| 使用部位: | branch-leaf |
| 功用: | To clear heat and disinhibit damp, calm liver and lower blood pressure, quicken blood and free network vessels. |
| 适用症: | Dysentery, diarrhea, dribbling pain of urination, hypertension, dizzy head and distention eyes, knocks and falls. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 27200-12-0 | 二氢杨梅素 | Dihydromyricetin | 161557 |
| 529-44-2 | 杨梅素 | Myricetin | 5281672 |
| 17912-87-7 | 杨梅苷 | Myricitrin | 5281673 |
| 117-39-5 | 槲皮素 | Quercetin | 5280343 |
| 522-12-3 | 槲皮苷 | Quercitrin | 5280459 |
| 17654-26-1 | 花旗松素（二氢槲皮素） | Taxifolin | 439533 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 28428076 |
| APOE | AD2; APO-E; ApoE4; LDLCQ5; LPG | 19q13.32 | 31036637 |
| CDK5 | LIS7; PSSALRE | 7q36.1 | 31163256 |
| COL11A2 | DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3 | 6p21.32 | 22251058 |
| GLP1R | GLP-1; GLP-1-R; GLP-1R | 6p21.2 | 28270518 |
| LATS1 | WARTS; wts | 6q25.1 | 30999669 |
| LATS2 | KPM | 13q12.11 | 30999669 |
| PIK3CD | APDS; IMD14; P110DELTA; PI3K; p110D | 1p36.22 | 21676539 |
| SPHK1 | SPHK | 17q25.1 | 22251058 |
| TREM2 | PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c | 6p21.1 | 31036637 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Cerebral Amyloid Angiopathy | disease | 31036637 |
| Cerebral Amyloid Angiopathy | disease | 28376923 |
| Choriocarcinoma | disease | 28428076 |
| Diabetes Mellitus, Experimental | disease | 28270518 |
| Liver neoplasms | group | 30999669 |
| Memory Disorders | disease | 28376923 |
| Neoplasm Invasiveness | phenotype | 28428076 |
| Neoplasms | group | 22251058 |
| Pancreatic Neoplasm | disease | 21676539 |
