1. 药材主信息
| 中文名称: | 川牛膝 |
| 英文名称: | root of Medicil cyathula |
| 拉丁名称: | Radix Cyathulae |
| 使用部位: | root |
| 功用: | To eliminate blood stasis and stimulate menstrual discharge, to allay arthralgia and ease the joint, and to relieve urinary disturbance. |
| 适用症: | Amenorrhea with concretion and conglomeration, retention of placenta, impediment pain in joints, hematuria, blood strangury, knocks and falls. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 1464-44-4 | 苯基-β-D-吡喃葡萄糖苷 | - | 65080 |
| 99-96-7 | 对羟基苯甲酸 | 4-Hydroxybenzoic acid | 135 |
| 3681-99-0 | - | 8-(beta-D-Glucopyranosyl)-4',7-dihydroxyisoflavone | 53384442 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 51068-94-1 | - | Betavulgarin | 442668 |
| 17086-76-9 | 杯苋甾酮 | Cyasterone | 119444 |
| 486-66-8 | 大豆苷元（黄豆苷元） | Daidzein | 5281708 |
| 552-66-9 | 大豆苷 | Daidzin | 107971 |
| 1135-24-6 | 阿魏酸 | Ferulic acid | 445858 |
| 446-72-0 | 染料木素 | Genistein | 5280961 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCA1 | ABC-1; ABC1; CERP; HDLCQTL13; HDLDT1; HPALP1; TGD | 9q31.1 | 26558782 |
| ABCG1 | ABC8; WHITE1 | 21q22.3 | 26558782 |
| APOE | AD2; APO-E; ApoE4; LDLCQ5; LPG | 19q13.32 | 26558782 |
| ARG1 | - | 6q23.2 | 31629735 |
| CEBPB | C/EBP-beta; IL6DBP; NF-IL6; TCF5 | 20q13.13 | 31629735 |
| CTBP1 | BARS; HADDTS | 4p16.3 | 29988033 |
| IL10 | CSIF; GVHDS; IL-10; IL10A; TGIF | 1q32.1 | 31629735 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 31629735 |
| IL6 | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 | 7p15.3 | 31629735 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 22931352 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Body Weight | phenotype | 21557739 |
| Fatty Liver | disease | 21557739 |
| Hypoxia | phenotype | 22743170 |
| Lung Neoplasms | group | 29988033 |
| Myocardial fibrosis | phenotype | 31629735 |
| Obesity | disease | 21557739 |
| Reperfusion Injury | disease | 22743170 |
| Ventricular Remodeling | phenotype | 31629735 |
