1. 药材主信息
| 中文名称: | 重楼排草 |
| 英文名称: | Parisshape Loosestrife |
| 拉丁名称: | Lysimachia paridiformis |
| 使用部位: | whole herb |
| 功用: | To dispel wind and eliminate damp, quicken blood and relieve pain, relieve cough, resolve toxin. |
| 适用症: | Wind-damp pain, pain in stomach duct and abdomen, cough, knocks and falls, clove sore and swollen boil, poisonous snake bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 480-44-4 | 金合欢素;刺槐素 | Acacetin | 5280442 |
| 490-46-0 | 表儿茶素 | EC;Epicatechin | 72276 |
| 491-70-3 | 木犀草素 | Luteolin | 5280445 |
| 19057-61-5 | - | Parillin | 197977 |
| 117-39-5 | 槲皮素 | Quercetin | 5280343 |
| 153-18-4 | 芦丁 | Rutin | 5280805 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 25281414 |
| HTR1A | 5-HT-1A; 5-HT1A; 5HT1a; ADRB2RL1; ADRBRL1; G-21; PFMCD | 5q12.3 | 31229563 |
| IFNG | IFG; IFI | 12q15 | 25281414 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 25281414 |
| KCNA5 | ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1 | 12p13.32 | 21906601 |
| MPO | - | 17q22 | 25281414 |
| PPARGC1A | LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1 | 4p15.2 | 28049156 |
| S100A8 | 60B8AG; CAGA; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; P8 | 1q21.3 | 25281414 |
| SIRT1 | SIR2; SIR2L1; SIR2alpha | 10q21.3 | 28049156 |
| STAT4 | SLEB11 | 2q32.2-q32.3 | 25281414 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Atrial Fibrillation | disease | 21906601 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Obesity | disease | 28049156 |
| Ventricular Remodeling | phenotype | 26185015 |
