1. 药材主信息
| 中文名称: | 炒枣仁 |
| 英文名称: | Prepared Spine Date Seed |
| 拉丁名称: | Semen Ziziphi Spinosae Preparata |
| 使用部位: | Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou |
| 功用: | Treatment of insomnia, dream-disturbed sleep, excessive sweating due to debility, thirst due to consumption of body fluid. |
| 适用症: | The chief components are jujuboside A and B. 1. Intraperitoneal injection its decoction ( 2.5-5.0g/kg ) exerts sedative and hypnotic effects in rats. 2. Intravenous injection of its decoction exerts significant and proloned hypotensive effect in anesthetized dogs. 3. Occasionally causing heart block. 4. Inducing hysterospasm. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 473-98-3 | 白桦脂醇 | Betulin | 72326 |
| 472-15-1 | 白桦脂酸 | Betulinic Acid | 64971 |
| 55466-05-2 | - | JujubosideB | 45358134 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AXL | ARK; JTK11; Tyro7; UFO | 19q13.2 | 30128052 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 28027595 |
| IL6 | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 | 7p15.3 | 28027595 |
| PRKAA1 | AMPK; AMPKa1 | 5p13.1 | 26776965 |
| PRKAA2 | AMPK; AMPK2; AMPKa2; PRKAA | 1p32.2 | 26776965 |
| PRKAB1 | AMPK; HAMPKb | 12q24.23 | 26776965 |
| SIRT1 | SIR2; SIR2L1; SIR2alpha | 10q21.3 | 26776965 |
| SREBF1 | SREBP1; bHLHd1 | 17p11.2 | 26776965 |
| STK11 | LKB1; PJS; hLKB1 | 19p13.3 | 26776965 |
| TNF | DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F | 6p21.33 | 28027595 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinogenesis | phenotype | 28027595 |
| Inflammation | phenotype | 28027595 |
| Liver neoplasms | group | 28027595 |
| Neoplasms, Experimental | phenotype | 28027595 |
| Obesity | disease | 28027595 |
