1. 药材主信息
| 中文名称: | 遍地锦 |
| 英文名称: | Wight’s StJohn’swort Equivalent plant: Hypericum e |
| 拉丁名称: | Hypericum wightianum |
| 使用部位: | whole herb |
| 功用: | To clear heat and resolve toxin, arrest diarrhea. |
| 适用症: | White mouth sore in children, infant pneumonia, stomatitis, mammary welling abscess, yellow-water sore, poisonous snake bites, diarrhea, enduring dysentery. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 26486-92-0 | 6-去氧异巴西红厚壳素 | 6-Deoxyisojacareubin | 5464641 |
| 11079-53-1 | 贯叶金丝桃素 | Hyperforin | 441298 |
| 548-04-9 | 金丝桃素 | Hypericin | 3663 |
| 117-39-5 | 槲皮素 | Quercetin | 5280343 |
| 153-18-4 | 芦丁 | Rutin | 5280805 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 25281414 |
| IFNG | IFG; IFI | 12q15 | 25281414 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 25281414 |
| LONP1 | CODASS; LON; LONP; LonHS; PIM1; PRSS15; hLON | 19p13.3 | 31683954 |
| MMP9 | CLG4B; GELB; MANDP2; MMP-9 | 20q13.12 | 20883786 |
| MPO | - | 17q22 | 25281414 |
| PPARGC1A | LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1 | 4p15.2 | 28049156 |
| S100A8 | 60B8AG; CAGA; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; P8 | 1q21.3 | 25281414 |
| SIRT1 | SIR2; SIR2L1; SIR2alpha | 10q21.3 | 28049156 |
| STAT4 | SLEB11 | 2q32.2-q32.3 | 25281414 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Neoplasms | group | 20883786 |
| Cerebellar Neoplasms | group | 20883786 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Glioblastoma | disease | 20883786 |
| Medulloblastoma | disease | 20883786 |
| Obesity | disease | 28049156 |
| Ventricular Remodeling | phenotype | 26185015 |
