1. 药材主信息
| 中文名称: | 白桔梗 |
| 英文名称: | Balloonflower root |
| 拉丁名称: | Radix Platycodi |
| 使用部位: | Platycodon grandiflorum (Jacq.) A. DC. |
| 功用: | Treatment of cough with much phlegm, sore throat, hoarseness of voice, lung abscess with purulent expectoration, absecess difficult to burst after suppuration. |
| 适用症: | 1. Small dosage of platycodoside, one of its active components, can increase secretion of respiratory tract and promote expectoration.2. Platycodoside may also serve as a sedative, an analgesic and an antipyretic.3. Its decoction inhibits the growth of Staphylococcus aureus and Bacillus typhoid in vitro. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 66779-34-8 | 桔梗皂苷A | 2''O-acetylplatycodin D | 46173910 |
| 66779-35-9 | 3’’-0-乙酰基-桔梗皂苷D | 3''O-acetylplatycodin D | 46173919 |
| 481-18-5 | α-菠菜甾醇 | alpha-Spinasterin | 5281331 |
| 473-98-3 | 白桦脂醇 | Betulin | 72326 |
| 58479-68-8 | 桔梗皂苷D | Platycodin D | 162859 |
| 58479-68-8 | 桔梗皂苷D | Platycodin D | 162859 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 28027595 |
| IL6 | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 | 7p15.3 | 28027595 |
| PRKAA1 | AMPK; AMPKa1 | 5p13.1 | 26776965 |
| PRKAA2 | AMPK; AMPK2; AMPKa2; PRKAA | 1p32.2 | 26776965 |
| PRKAB1 | AMPK; HAMPKb | 12q24.23 | 26776965 |
| SIRT1 | SIR2; SIR2L1; SIR2alpha | 10q21.3 | 26776965 |
| SREBF1 | SREBP1; bHLHd1 | 17p11.2 | 26776965 |
| STK11 | LKB1; PJS; hLKB1 | 19p13.3 | 26776965 |
| TNF | DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F | 6p21.33 | 28027595 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinogenesis | phenotype | 28027595 |
| Inflammation | phenotype | 28027595 |
| Liver neoplasms | group | 28027595 |
| Neoplasms, Experimental | phenotype | 28027595 |
| Obesity | disease | 28027595 |
