CAS号:10338-51-9-红景天苷 - Salidroside-科华智慧

1. 主信息

英文名:	Salidroside
中文名:	红景天苷
CAS编号:	10338-51-9
化学分子式：	C₁₄H₂₀O₇
化学分子量：	300.30 g/mol
SMILES：	C1=CC(=CC=C1CCOC2C(C(C(C(O2)CO)O)O)O)O
来源：	木通女贞地黄独一味大花红景天
结构类型：	苯乙醇类
其它名称或标识：	beta-D-glucopyranoside, 2-(4-hydroxyphenyl)ethyl- rhodioloside rhodosin salidroside salidroside, (-)-

2. 供应商与价格

供应商	包装规格	含量	价格(元)	购买	环境要求	货期	说明
科华智慧	20mg	HPLC≥98%	80	点击购买	2-8℃	现货	-
科华智慧	100mg	HPLC≥98%	259	点击购买	2-8℃	现货	-
科华智慧	400mg	HPLC≥98%	800	点击购买	2-8℃	现货	-
科华智慧	1g	≥98%	960	点击购买	2-8℃	现货	-
科华智慧	5g	≥98%	2240	点击购买	2-8℃	现货	-
科华智慧	25g	≥98%	7840	点击购买	2-8℃	现货	-

回顶

3. 结构

3.1 二维结构

3.2 三维结构

-1 -2 -3 41 42 0 1 0 0 0 0 0999 V2000 -1.4866 -0.8508 0.2140 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0554 0.5701 1.2374 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.6353 2.3265 -1.2542 O 0 0 0 0 0 0 0 0 0 0 0 0 -4.8370 -0.3008 -1.1594 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.7935 2.7009 1.0148 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.3280 -3.4654 0.1043 O 0 0 0 0 0 0 0 0 0 0 0 0 5.1313 0.2170 -2.4698 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.2869 1.3289 -0.2930 C 0 0 1 0 0 0 0 0 0 0 0 0 -3.4512 -0.0407 -0.9522 C 0 0 1 0 0 0 0 0 0 0 0 0 -1.8475 1.5504 0.1717 C 0 0 2 0 0 0 0 0 0 0 0 0 -2.8557 -1.1420 -0.0718 C 0 0 1 0 0 0 0 0 0 0 0 0 -1.3284 0.3509 0.9646 C 0 0 1 0 0 0 0 0 0 0 0 0 -2.9025 -2.5024 -0.7603 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6125 -0.5066 1.9749 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0851 -0.2303 2.2578 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8999 -0.1105 0.9929 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4842 -1.2444 0.4517 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0487 1.1313 0.3960 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2374 -1.1337 -0.7171 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8019 1.2422 -0.7729 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3962 0.1096 -1.3295 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.9854 1.4486 0.5444 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9684 -0.0312 -1.9371 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1981 1.7563 -0.6874 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.3999 -1.2243 0.8790 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8562 0.2649 1.9242 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3242 -2.5012 -1.6902 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.9286 -2.8084 -0.9836 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.5484 2.1502 -1.5388 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.2725 -0.3184 -0.2902 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3651 2.5379 1.7845 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0788 -0.6136 2.9265 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5197 -1.4450 1.4156 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1824 0.7005 2.8316 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4976 -1.0252 2.8912 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.4186 -3.1808 0.2989 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3642 -2.2169 0.9203 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5906 2.0197 0.8211 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6948 -2.0237 -1.1408 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9220 2.2134 -1.2452 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4672 -0.6630 -2.7123 H 0 0 0 0 0 0 0 0 0 0 0 0 1 11 1 0 0 0 0 1 12 1 0 0 0 0 2 12 1 0 0 0 0 2 14 1 0 0 0 0 3 8 1 0 0 0 0 3 29 1 0 0 0 0 4 9 1 0 0 0 0 4 30 1 0 0 0 0 5 10 1 0 0 0 0 5 31 1 0 0 0 0 6 13 1 0 0 0 0 6 36 1 0 0 0 0 7 21 1 0 0 0 0 7 41 1 0 0 0 0 8 9 1 0 0 0 0 8 10 1 0 0 0 0 8 22 1 0 0 0 0 9 11 1 0 0 0 0 9 23 1 0 0 0 0 10 12 1 0 0 0 0 10 24 1 0 0 0 0 11 13 1 0 0 0 0 11 25 1 0 0 0 0 12 26 1 0 0 0 0 13 27 1 0 0 0 0 13 28 1 0 0 0 0 14 15 1 0 0 0 0 14 32 1 0 0 0 0 14 33 1 0 0 0 0 15 16 1 0 0 0 0 15 34 1 0 0 0 0 15 35 1 0 0 0 0 16 17 2 0 0 0 0 16 18 1 0 0 0 0 17 19 1 0 0 0 0 17 37 1 0 0 0 0 18 20 2 0 0 0 0 18 38 1 0 0 0 0 19 21 2 0 0 0 0 19 39 1 0 0 0 0 20 21 1 0 0 0 0 20 40 1 0 0 0 0

回顶

4. 国际命名与标识

4.1 IUPAC Name

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol

4.2 InChl

InChI=1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1

4.3 InChlKey

ILRCGYURZSFMEG-RKQHYHRCSA-N

4.4 Canonical SMILES

C1=CC(=CC=C1CCOC2C(C(C(C(O2)CO)O)O)O)O

4.5 lsomeric SMILES

C1=CC(=CC=C1CCO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O

4.6 SDF文件

                  0  0  0     0  0            999 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 1
M  V30 BEGIN ATOM
M  V30 1 C -3.4641 -4.73233e-15 0 0
M  V30 2 C -4.33013 0.5 0 0
M  V30 3 C -4.33013 1.5 0 0
M  V30 4 C -3.4641 2 0 0
M  V30 5 C -2.59808 1.5 0 0
M  V30 6 C -2.59808 0.5 0 0
M  V30 7 C -1.73205 -3.1225e-15 0 0
M  V30 8 C -1.73205 -1 0 0
M  V30 9 O -0.866025 -1.5 0 0
M  V30 10 C 7.9203e-16 -1 0 0
M  V30 11 C 0.866025 -1.5 0 0
M  V30 12 C 1.73205 -1 0 0
M  V30 13 C 1.73205 4.44089e-16 0 0
M  V30 14 C 0.866025 0.5 0 0
M  V30 15 O 0 0 0 0
M  V30 16 C 0.866025 1.5 0 0
M  V30 17 O 1.73205 2 0 0
M  V30 18 O 2.59808 0.5 0 0
M  V30 19 O 2.59808 -1.5 0 0
M  V30 20 O 0.866025 -2.5 0 0
M  V30 21 O -5.19615 2 0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 6
M  V30 2 2 1 2
M  V30 3 1 2 3
M  V30 4 2 3 4
M  V30 5 1 3 21
M  V30 6 1 4 5
M  V30 7 2 5 6
M  V30 8 1 6 7
M  V30 9 1 7 8
M  V30 10 1 8 9
M  V30 11 1 9 10
M  V30 12 1 10 15
M  V30 13 1 10 11
M  V30 14 1 11 12
M  V30 15 1 11 20
M  V30 16 1 12 13
M  V30 17 1 12 19
M  V30 18 1 13 14
M  V30 19 1 13 18
M  V30 20 1 14 15
M  V30 21 1 14 16
M  V30 22 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END

回顶

5. 波谱数据

5.1 ¹³C核磁共振谱(¹³C NMR)

5.2 ¹H核磁共振谱(¹H NMR)

5.3 质谱(MS)

补充中

5.4 红外光谱(IR)

补充中

5.5 紫外/可见光谱(UV/Vis)

补充中

回顶

6. 相关药材

中文名称	英文名称	拉丁文名称
草苁蓉	Boschniakia Rossica Herba	-
大花红景天	Bigflower Rhodiola	Rhodiola crenulata [Syn. Rhodiola euryphylla]
大血藤	Stem of Sargentgloryvine	Caulis Sargentodoxae
地黄	Radix Rehmanniae	-
独一味	Common Lamiophlomis	Lamiophlomis rotata [Syn. Phlomis rotata ]
飞廉	Curly Bristlethistle Equivalent plant: Carduus aca	Carduus crispus
红景天	all - grass of Rhodiola	Radix et Rhizoma Rhodiolae
互生红景天	Oppositeleaf Rhodiola	Rhodiola subopposita
黄芩	root of Baikal skullcap	Radix Scutellariae
吉氏红景天	Algid Rhodiola	Rhodiola algida

回顶

7. 相关靶点

基因靶点	靶点位置	参考文献
ADORA2A	22q11.23	25772255
AKT1	14q32.33	24471788
AKT1	14q32.33	25754463
AKT1	14q32.33	31251107
BAX	19q13.33	24471788
BAX	19q13.33	25772255
BCL2	18q21.33	25772255
BCL2L1	20q11.21	24471788
BCL2L1	20q11.21	29723606
CASP9	1p36.21	25772255

回顶

8. 相关疾病

疾病名称	疾病类型	参考文献
Alzheimer's Disease	disease	27933142
Brain Ischemia	disease	29426336
Cancer cachexia	disease	27493875
Diabetes Mellitus, Experimental	disease	30624028
Diabetes Mellitus, Experimental	disease	25754463
Diabetic Retinopathy	disease	31251107
Hyperglycemia	disease	30624028
Hypoxia	phenotype	30396856
Hypoxia	phenotype	25772255
Insulin Resistance	phenotype	25754463

回顶