1. 药材主信息
| 中文名称: | 飞廉 |
| 英文名称: | Curly Bristlethistle Equivalent plant: Carduus aca |
| 拉丁名称: | Carduus crispus |
| 使用部位: | root or whole herb |
| 功用: | To dispel wind, clear heat, disinhibit damp, cool blood and stanch bleeding, quicken blood and disperse swelling. |
| 适用症: | Common cold with cough, headache and dizziness, infection of urinary system, chyluria, vaginal discharge, jaundice, wind-heat impediment pain, blood ejection, spontaneous external bleeding, hematuria, profuse menstruation, dysfunctional uterine bleeding, knocks and falls, clove sore and swollen boil, toxin swelling from hemorrhoids, scalds. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 2196-18-1 | β-Hydroxypropiovanillone | 3-Hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-1-propanone | 75142 |
| 136196-47-9 | 3,4'-Dihydroxy-3',5'-dimethoxypropiophenone | 3-Hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)propan-1-one | 54353627 |
| 5973-06-8 | 软脂酸-β-香树精酯 | beta-Amyrin palmitate | 13915599 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 63596-94-1 | - | Cudranone | 191694 |
| 118-34-3 | 紫丁香苷 | Eleutheroside B | 5316860 |
| 10338-51-9 | 红景天苷 | Salidroside | 159278 |
| 83-48-7 | 豆甾醇 | Stigmasterol | 5280794 |
| 134-96-3 | 丁香醛 | Syringaldehyde | 8655 |
| 109194-60-7 | Tachioside | Tachioside | 11962143 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| ADORA2A | A2aR; ADORA2; RDC8 | 22q11.23 | 25772255 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24471788 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25754463 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31251107 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 27933142 |
| Brain Ischemia | disease | 29426336 |
| Cancer cachexia | disease | 27493875 |
| Diabetes Mellitus, Experimental | disease | 30624028 |
| Diabetes Mellitus, Experimental | disease | 25754463 |
| Diabetic Retinopathy | disease | 31251107 |
| Hyperglycemia | disease | 30624028 |
| Hypoxia | phenotype | 30396856 |
| Hypoxia | phenotype | 25772255 |
| Insulin Resistance | phenotype | 25754463 |
