1. 药材主信息
| 中文名称: | 独一味 |
| 英文名称: | Common Lamiophlomis |
| 拉丁名称: | Lamiophlomis rotata [Syn. Phlomis rotata ] |
| 使用部位: | whole herb |
| 功用: | To quicken blood and transform stasis, disperse swelling and relieve pain. |
| 适用症: | Knocks and falls, pain in sinews and bones, swelling pain in joints, dysmenorrhea, flooding and spotting. |
| 毒副作用: | Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 490-79-9 | 2,5-二羟基苯甲酸(龙胆酸) | 2,5-Dihydroxybenzoic acid | 3469 |
| 99-50-3 | 原儿茶酸 | 3,4-Dihydroxybenzoic acid | 72 |
| 480-44-4 | 金合欢素;刺槐素 | Acacetin | 5280442 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 578-74-5 | 芹菜素-7-O-β-D-吡喃葡萄糖苷;大波斯菊苷 | Apigetrin | 5280704 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 331-39-5 | 咖啡酸 | Caffeic Acid | 689043 |
| 81525-13-5 | 连翘酯苷B | Forsythoside B | 23928102 |
| 437-64-9 | 芫花素 | Genkwanin | 5281617 |
| 10597-60-1 | 羟基酪醇 | Hydroxytyrosol | 82755 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ADORA2A | A2aR; ADORA2; RDC8 | 22q11.23 | 25772255 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24471788 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25754463 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31251107 |
| ATF2 | CRE-BP1; CREB-2; CREB2; HB16; TREB7 | 2q31.1 | 25787271 |
| BAX | BCL2L4 | 19q13.33 | 24471788 |
| BAX | BCL2L4 | 19q13.33 | 25772255 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21871133 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 25772255 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Alveolar Bone Loss | disease | 31943455 |
| Alzheimer's Disease | disease | 27933142 |
| Atrial Fibrillation | disease | 21906601 |
| Blood Pressure | phenotype | 28143892 |
| Blood Pressure | phenotype | 25076013 |
| Brain Ischemia | disease | 29426336 |
| Cancer cachexia | disease | 27493875 |
| Colorectal Neoplasms | group | 23824743 |
| Diabetes Mellitus, Experimental | disease | 30624028 |