1. 靶点主信息
| NCBI Gene id: | 114548 |
| Gene_name: | NLRP3 |
| Gene alias: | AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; FCU; KEFH; MWS; NALP3; PYPAF1 |
| Map location: | 1q44 |
| Type of gene: | protein-coding |
| Description: | NLR family pyrin domain containing 3 |
| OMIM_id: | 606416 |
| HGNC_id: | 16400 |
| Ensembl_id: | ENSG00000162711 |
2. 相关药材
| 中文名称 | 英文名称 | 拉丁文名称 |
| 安息香 | Benzoin | Benzoinum |
| 按叶 | Eucalyptus Leaf | Eucalyptus globulus |
| 凹叶厚朴 | Twolobed Officinal Mangolia | Magnolia biloba |
| 凹叶瑞香 | Retuseleaf Daphne | Daphne retusa |
| 八角茴香 | Chinese Star Anise | Fructus Anisi Stellati |
| 白鲳 | Drug Sweetflag | Acorus calamus |
| 百合 | Bulb of Greenish Lily | Bulbus Lilii |
| 百合花 | Flos Lilii brownii | - |
| 百合子 | Semen Lilii brownii | - |
| 白花丹参 | Whiteflower Danshen | Salvia miltiorrhiza f. alba |
3. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 480-41-1 | - | (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one | 667495 |
| 18956-16-6 | 小豆蔻明 | Cardamonin | 641785 |
| 64-86-8 | 秋水仙碱 | Colchicine | 6167 |
| 3486-66-6 | 黄连碱 | Coptisine | 72322 |
| 4547-24-4 | 科罗索酸 | Corosolic acid | 6918774 |
| 458-37-7 | 姜黄素 | Curcumin | 969516 |
| 486-35-1 | 瑞香素;祖师麻甲素 | Daphnetin | 5280569 |
| 989-51-5 | 表没食子儿茶素没食子酸酯 | Epigallocatechin Gallate | 65064 |
| 470-82-6 | 桉油精；桉叶素 | Eucalyptol | 2758 |
| 35354-74-6 | 和厚朴酚 | Honokiol | 72303 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acne Vulgaris | disease | 22763784 |
| Acute Coronary Syndrome | disease | 23265346 |
| Acute Coronary Syndrome | disease | 29055633 |
| Acute Coronary Syndrome | disease | 27129183 |
| Acute kidney injury | disease | 31034781 |
| Acute Lung Injury | disease | 31186013 |
| Acute Lung Injury | disease | 28285192 |
| Acute Lung Injury | disease | 21279327 |
| Adenocarcinoma | group | 25499851 |
| Adenomatous Polyposis Coli | disease | 20971552 |
