1. 药材主信息
| 中文名称: | 竹节三七 |
| 英文名称: | Japanese Ginseng |
| 拉丁名称: | Panax pseudo - ginseng var. japonicus |
| 使用部位: | rhizome |
| 功用: | To supplement vacuity, relieve cough and dispel phlegm, stanch bleeding and dissipate stasis, disperse swelling and relieve pain. |
| 适用症: | Weakness during convalescence, inappetence, vacuity taxation cough, hemoptysis, blood ejection, spontaneous external bleeding, hematochezia, hematuria, aberratio mensium, flooding and spotting, bleeding due to external injury, concretion and conglomeration, amenorrhea due to blood stasis, postpartum stasis stagnation abdominal pain, knocks and falls, pain in joints due to rheumatalgia, swollen welling abscess, hemorrhoids, poisonous snake bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 52286-59-6 | 人参皂苷Re | Ginsenoside B2 | 441921 |
| 41753-43-9 | 人参皂苷Rb1 | Ginsenoside Rb1 | 9898279 |
| 68406-26-8 | - | Ginsenoside Rb3 | 12912363 |
| 34367-04-9 | 人参皂苷Ro | Ginsenoside Ro | 11815492 |
| 88100-04-3 | 三七皂苷Fa | Notoginsenoside Fa | 75054973 |
| 88100-04-3 | 三七皂苷Fa | Notoginsenoside Fa | 75054973 |
| 87741-78-4 | - | Notoginsenoside R6 | 101170141 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 23170834 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 30394318 |
| ATG3 | APG3; APG3-LIKE; APG3L; PC3-96 | 3q13.2 | 31094028 |
| ATG5 | APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 | 6q21 | 31094028 |
| ATG7 | APG7-LIKE; APG7L; GSA7 | 3p25.3 | 31094028 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 30394318 |
| CYBB | AMCBX2; CGD; GP91-1; GP91-PHOX; GP91PHOX; IMD34; NOX2; p91-PHOX | Xp21.1-p11.4 | 24571453 |
| DECR1 | DECR; NADPH; SDR18C1 | 8q21.3 | 24571453 |
| ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | 6q25.1-q25.2 | 23170834 |
| GSK3B | - | 3q13.33 | 23321003 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 23321003 |
| Alzheimer's Disease | disease | 30394318 |
| Brain Edema | phenotype | 21647765 |
| Brain Infarction | disease | 21647765 |
| Diabetic Retinopathy | disease | 30832367 |
| Endotoxemia | phenotype | 23170834 |
| Infarction, Middle Cerebral Artery | disease | 21647765 |
| Inflammation | phenotype | 30832367 |
| Inflammation | phenotype | 23170834 |
| Inflammation | phenotype | 31094028 |
