1. 药材主信息
| 中文名称: | 皂荚 |
| 英文名称: | Chinese Honeylocust |
| 拉丁名称: | Gleditsia sinensis [Syn. Gleditsia horrida] |
| 使用部位: | fruit |
| 功用: | To relieve cough and dispel phlegm, open orifices, kill worms and dissipate binds. |
| 适用症: | Cough of phlegm asthma, wind stroke clenched jaw, phlegm-drool and congesting lung, clouded spirit with loss of speech, epilepsy, throat impediment, urinary and fecal stoppage, swollen welling abscess, scab and lichen. |
| 毒副作用: | Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 506-52-5 | 1-二十六烷醇 | 1-Hexacosanol | 68171 |
| 10091-84-6 | - | 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine | 135438588 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 29702-25-8 | 异牡荆苷：异牡荆素 | Isovitexin | 162350 |
| 630-03-5 | 正二十九烷 | Nonacosane | 12409 |
| 79103-90-5 | 瓜子金皂苷XXXI | Onjisaponin F | 10701737 |
| 83-48-7 | 豆甾醇 | Stigmasterol | 5280794 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| E2F1 | E2F-1; RBAP1; RBBP3; RBP3 | 20q11.22 | 31208440 |
| FOXM1 | FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT | 12p13.33 | 31208440 |
| NR1H2 | LXR-b; LXRB; NER; NER-I; RIP15; UNR | 19q13.33 | 24107776 |
| NR1H3 | LXR-a; LXRA; RLD-1 | 11p11.2 | 24107776 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Liver diseases | group | 24107776 |
| Liver neoplasms | group | 31208440 |
