1. 药材主信息
| 中文名称: | 鸦片 |
| 英文名称: | Opium |
| 拉丁名称: | Papaver somniferum |
| 使用部位: | latex from unripe capsules |
| 功用: | To relieve pain, astringe intestines, suppress cough. |
| 适用症: | Pain in heart and abdomen, chronic diarrhea, chronic dysentery, dry cough without phlegm. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 2308-85-2 | 软脂酸谷甾醇酯 | - | 9852570 |
| 5140-39-6 | - | (5bR,12bS,14S)-5b,6,7,8,12b,14-Hexahydro-10,11,14-trimethoxy-1,3-dioxolo(7,8)(2)benzopyrano(3,4-a)(3)benzazepine | 12309624 |
| 261613-72-3 | - | (R)-nonacosan-10-ol | 342803 |
| 2688-77-9 | - | (S)-Laudanosine | 73397 |
| 483-34-1 | 四氢非洲防己碱 | (S)-Tetrahydrocolumbamine | 440229 |
| 14755-02-3 | 反式-3-羟基肉桂酸 | 3'-Hydroxycinnamic acid | 637541 |
| 18694-10-5 | - | 5-[(6,7-Dimethoxyisoquinolin-1-yl)methyl]-2-methoxyphenol | 167736 |
| 73030-71-4 | 白术内酯III | Atractylenolide III | 155948 |
| 124-97-0 | - | CID 18477544 | 18477544 |
| 21040-59-5 | - | Codamine | 20056510 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27154977 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31819036 |
| ASAH1 | AC; ACDase; ASAH; PHP; PHP32; SMAPME | 8p22 | 30735839 |
| ATG5 | APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 | 6q21 | 26472194 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 31163195 |
| BCL2L11 | BAM; BIM; BOD | 2q13 | 31817696 |
| CCND1 | BCL1; D11S287E; PRAD1; U21B31 | 11q13.3 | 31163195 |
| EIF4A1 | DDX2A; EIF-4A; EIF4A; eIF-4A-I; eIF4A-I | 17p13.1 | 31402318 |
| GSK3B | - | 3q13.33 | 27154977 |
| HIF1A | HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 | 14q23.2 | 31819036 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Neoplasms | group | 26472194 |
| Glioma | disease | 26472194 |
| leukemia | disease | 27154977 |
| Liver neoplasms | group | 31163195 |
| Prostatic Neoplasms | group | 30735839 |
