1. 药材主信息
| 中文名称: | 雪莲 |
| 英文名称: | Snow Lotus |
| 拉丁名称: | Saussurea involucrata |
| 使用部位: | whole herb with flower |
| 功用: | To warm kidney and invigorate yang , dispel wind and overcome damp, quicken blood and free menstruation. |
| 适用症: | Impotence, weakness in lumbus and knees, wind-damp impediment pain, menstrual disorder, amenorrhea, uterus cold and abdominal pain, cold rheum cough. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 6765-39-5 | 1-十七碳烯 | 1-Heptadecene | 23217 |
| 99-93-4 | 4'-羟基苯乙酮 | 4'-Hydroxyacetophenone | 7469 |
| 502-69-2 | 植酮 | 6,10,14-Trimethylpentadecan-2-one | 10408 |
| 502-69-2 | 植酮 | 6,10,14-Trimethylpentadecan-2-one | 10408 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 578-74-5 | 芹菜素-7-O-β-D-吡喃葡萄糖苷;大波斯菊苷 | Apigetrin | 5280704 |
| 7770-78-7 | 牛蒡子苷元 | Arctigenin | 64981 |
| 20362-31-6 | 牛蒡子苷 | Arctiin | 100528 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 3625-52-3 | - | Dotriacontanoic acid | 19255 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26335809 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21871133 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 21871133 |
| BCL2L11 | BAM; BIM; BOD | 2q13 | 31817696 |
| CAT | - | 11p13 | 29179721 |
| CAT | - | 11p13 | 24559844 |
| CD274 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 | 9p24.1 | 27378243 |
| CDC37 | P50CDC37 | 19p13.2 | 21871133 |
| CDK4 | CMM3; PSK-J3 | 12q14.1 | 21871133 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Asthma | disease | 26335809 |
| Blood Pressure | phenotype | 28143892 |
| Body Weight | phenotype | 24559844 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Epstein-Barr Virus Infections | group | 28056971 |
| Fibrosis | phenotype | 28143892 |
