科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 香茶菜
英文名称: Common Rabdosia
拉丁名称: Isodon amethystoides
使用部位: aerial parts or root
功用: Aerial parts: To clear heat and disinhibit damp, quicken blood and dissipate stasis, resolve toxin and disperse swelling; Root: To clear heat and resolve toxin, dispel stasis and relieve pain.
适用症: Aerial parts: Damp-heat jaundice, strangury, edema, swelling pain in throat, impediment pain in joints, menstrual block, mammary welling abscess, hemorrhoids, effusion of back, knocks and falls, poisonous snake bite; Root: Poisonous snake bites, swelling toxin of sore and boil, aching sinews and bones, knocks and falls, burns and scalds.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
71850-15-2 脱氢山楂酸 Camaldulenic acid 10528366
53155-25-2 蔷薇酸 Euscaphic acid 471426
128397-09-1 山香二烯酸 Hyptadienic acid 14605533
4373-41-5 山楂酸 Maslinic Acid 73659
4373-41-5 山楂酸 Maslinic Acid 73659
508-02-1 齐墩果酸 Oleanolic Acid 10494
22384-63-0 胡麻素 Pedalitin 31161
83-48-7 豆甾醇 Stigmasterol 5280794
530-57-4 丁香酸 Syringic acid 10742

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCB11 ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP 2q31.1 24107776
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 24107776
ABCG5 STSL; STSL2 2p21 24107776
ABCG8 GBD4; STSL; STSL1 2p21 24107776
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 21168456
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 21708244
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 24000005
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 27472952
APP AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 21q21.3 24107941
BACE1 ASP2; BACE; HSPC104 11q23.3 24107941

4. 相关疾病