1. 药材主信息
| 中文名称: | 西洋参 |
| 英文名称: | American Ginseng |
| 拉丁名称: | Radix Pacis quinquefolii |
| 使用部位: | root |
| 功用: | 1. To replenish qi and promote body fluids; 2. To nourish yin and clear heat |
| 适用症: | Qi vacuity, yin depletion and effulgent fire, cough and asthma with phlegm-blood, vacuity heat and vexation fatigue, diabetes mellitus due to internal heat, thirst with dry throat. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 502-61-4 | α－法呢烯 | - | 5281516 |
| 495-61-4 | (-)-β-bisabolene | - | 10104370 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 28976-67-2 | - | (-)-beta-Curcumene | 14014430 |
| 17334-55-3 | - | (1aR,7R,7aR,7bS)-1,1,7,7a-tetramethyl-2,3,5,6,7,7b-hexahydro-1aH-cyclopropa[a]naphthalene | 15560278 |
| 80952-71-2 | (R型)人参皂苷Rh1 | (20R)-Ginsenoside Rh1 | 21599923 |
| 30636-90-9 | (S型)原人参二醇 | (20S)-Protopanaxadiol | 11213350 |
| 8002-43-5 | - | (2S)-2-amino-3-[[(2R)-2-butanoyloxy-3-propanoyloxypropoxy]-hydroxyphosphoryl]oxypropanoic acid | 6323481 |
| 115939-25-8 | 丹酚酸B | (R)-2-(((2R,3R)-4-((E)-3-((R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carbonyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid | 11629084 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30813295 |
| ATG3 | APG3; APG3-LIKE; APG3L; PC3-96 | 3q13.2 | 31094028 |
| ATG5 | APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 | 6q21 | 31094028 |
| ATG7 | APG7-LIKE; APG7L; GSA7 | 3p25.3 | 31094028 |
| BAK1 | BAK; BAK-LIKE; BCL2L7; CDN1 | 6p21.31 | 24622841 |
| BAX | BCL2L4 | 19q13.33 | 21194832 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21194832 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 24622841 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 24622841 |
| CYBB | AMCBX2; CGD; GP91-1; GP91-PHOX; GP91PHOX; IMD34; NOX2; p91-PHOX | Xp21.1-p11.4 | 24571453 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 23321003 |
| Brain Edema | phenotype | 21647765 |
| Brain Infarction | disease | 21647765 |
| Colorectal Neoplasms | group | 21194832 |
| Corneal Neovascularization | disease | 29465315 |
| Infarction, Middle Cerebral Artery | disease | 21647765 |
| Inflammation | phenotype | 31094028 |
| Insulin Resistance | phenotype | 22571876 |
| Longevity | phenotype | 21844359 |
| Lung Neoplasms | group | 29061506 |
