科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 乌梅
英文名称: Smoked Plum
拉丁名称: Fructus Mume
使用部位: unripe fruit
功用: To arrest persistent cough, to relieve diarrhea by astringing the intestines, to promote the production of body fluid, and to relieve colic caused by ascaris.
适用症: Enduring cough, chronic diarrhea and dysentery, hematuria, hematochezia, flooding and spotting, vacuity heat with vexation and thirst, roundworm reversal with abdominal pain, outcrop of sore and welling abscess.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
7785-53-7 - (+)-alpha-Terpineol 442501
507-70-0 - (+)-Isoborneol 6973640
1118-12-3 - (1,1-Dimethylethyl)urea 14233
1118-12-3 - (1,1-Dimethylethyl)urea 14233
480-41-1 - (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one 667495
97-67-6 L-苹果酸 (2S)-2-Hydroxybutanedioic acid 222656
486459-98-7 SITAGLIPTIN DEFUORO IMPURITY 4 (R)-b-(Boc-amino)-2,5-difluorobenzenebutanoic acid 11347588
28549-12-4 S-(-)-苯乙醇腈 (S)-Mandelonitrile 439767
634-36-6 1,2,3-三甲氧基苯 1,2,3-Trimethoxybenzene 12462
83-33-0 1-二氢茚酮 1-Indanone 6735

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCB11 ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP 2q31.1 24107776
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 24107776
ABCG5 STSL; STSL2 2p21 24107776
ABCG8 GBD4; STSL; STSL1 2p21 24107776
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 27710830
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 21168456
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 21708244
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 24000005
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 27472952
APP AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 21q21.3 24107941

4. 相关疾病