1. 药材主信息
| 中文名称: | 乌桕木根皮 |
| 英文名称: | Chinese Tallowtree Bark |
| 拉丁名称: | Sapium sebiferum |
| 使用部位: | root cortex |
| 功用: | To drain precipitation and expel water, dissipate binds and disperse swelling, resolve snake toxin, lower blood pressure. |
| 适用症: | Edema, ascites, urinary and fecal st oppage, hypertension, concretion conglomeration accumulation and gathering, painful swelling from clove sore, eczema, scab and lichen, poisonous snake bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 26791-72-0 | - | (3aR,7S,8aR)-6-((1R)-1-(Acetyloxy)-3-oxobutyl)-3,3a,4,7,8,8a-hexahydro-7-methyl-3-methylene-2H-cyclohepta(b)furan-2-one | 442335 |
| 13059-96-6 | - | Coriose | 192877 |
| 149-91-7 | 没食子酸 | Gallic Acid | 370 |
| 35287-72-0 | - | Secalonic acid A | 169680 |
| 90-24-4 | 4',6-二甲基-2-羟基苯乙酮 | Xanthoxylin | 66654 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 29235094 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 29235094 |
| ACACA | ACAC; ACACAD; ACC; ACC1; ACCA | 17q12 | 30630510 |
| CYP7A1 | CP7A; CYP7; CYPVII | 8q12.1 | 29235094 |
| CYP7B1 | CBAS3; CP7B; SPG5A | 8q12.3 | 29235094 |
| GSK3B | - | 3q13.33 | 30630510 |
| KEAP1 | INrf2; KLHL19 | 19p13.2 | 30630510 |
| NFE2L2 | HEBP1; IMDDHH; NRF2; Nrf-2 | 2q31.2 | 30630510 |
| NR1H4 | BAR; FXR; HRR-1; HRR1; PFIC5; RIP14 | 12q23.1 | 29235094 |
| PRKAA1 | AMPK; AMPKa1 | 5p13.1 | 30630510 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 30447302 |
| Cholestasis | disease | 29235094 |
| Liver Failure, Acute | disease | 30630510 |
