1. 药材主信息
| 中文名称: | 土木香 |
| 英文名称: | Elecampane Inula Equivalent plant: Inula racemosa |
| 拉丁名称: | Inula helenium |
| 使用部位: | root |
| 功用: | To fortify spleen and harmonize stomach, regulate qi and resolve depression, relieve pain and quiet fetus. |
| 适用症: | Distending pain in chest and rib-side, distending pain in stomach duct, vomiting and diarrhea, contusion in chest and rib-side, forking qi with pain, stirring fetus in pregnancy. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 352438-71-2 | ACETALDEHYDE-D4 DIETHYL ACETAL | Acetal | 7765 |
| 546-43-0 | 土木香内酯 | Alantolactone | 72724 |
| 41546-34-3 | D-手性肌醇 | Inositol | 892 |
| 470-17-7 | 异土木香内酯 | Isoalantolactone | 73285 |
| 470-17-7 | 异土木香内酯 | Isoalantolactone | 73285 |
| 637-50-3 | β-甲基苯乙烯 | trans-beta-Methylstyrene | 252325 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| BAX | BCL2L4 | 19q13.33 | 28914393 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 28914393 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 28914393 |
| CASP7 | CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3 | 10q25.3 | 28914393 |
| CDK2 | CDKN2; p33(CDK2) | 12q13.2 | 21421237 |
| CDKN1A | CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 | 6p21.2 | 21421237 |
| CYCS | CYC; HCS; THC4 | 7p15.3 | 28701209 |
| DDR2 | MIG20a; NTRKR3; TKT; TYRO10; WRCN | 1q23.3 | 27148686 |
| HES1 | HES-1; HHL; HRY; bHLHb39 | 3q29 | 31621893 |
| IKBKB | IKK-beta; IKK2; IKKB; IMD15; IMD15A; IMD15B; NFKBIKB | 8p11.21 | 28701209 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Neoplasms | group | 27148686 |
| Breast Carcinoma | disease | 24028602 |
| Colonic Neoplasms | group | 29037867 |
| Glioblastoma | disease | 27148686 |
| Glioblastoma Multiforme | disease | 28701209 |
| Infarction, Middle Cerebral Artery | disease | 31323885 |
| Micronuclei, Chromosome-Defective | phenotype | 28914393 |
| Prostatic Neoplasms | group | 21421237 |
