1. 药材主信息
| 中文名称: | 通关藤 |
| 英文名称: | Tenacious Condorvine |
| 拉丁名称: | Marsdenia tenacissima |
| 使用部位: | stem, root or leaf |
| 功用: | To clear heat and resolve toxin, relieve cough and calm asthma, disinhibit damp and free milk, anticancer. |
| 适用症: | swelling pain in throat, lung heat cough asthma, damp-heat jaundice, inhibited urination [=dysuria], breast milk stoppage, sore and boil, carcinoma. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 579-04-4 | - | D-Cymarose | 5461156 |
| 492-62-6 | - | D-Glucose | 5793 |
| 628-97-7 | 棕榈酸乙酯 | Ethyl palmitate | 12366 |
| 630-04-6 | 三十一烷 | Hentriacontane | 12410 |
| 57-10-3 | 棕榈酸 | Palmitic Acid | 985 |
| 88-99-3 | 邻苯二甲酸 | Phthalic acid | 1017 |
| 474-58-8 | 刺五加苷A(胡萝卜苷） | Sitogluside | 5742590 |
| 57-11-4 | 硬脂酸 | Stearic Acid | 5281 |
| 83-48-7 | 豆甾醇 | Stigmasterol | 5280794 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| CTBP1 | BARS; HADDTS | 4p16.3 | 29988033 |
| MMP3 | CHDS6; MMP-3; SL-1; STMY; STMY1; STR1 | 11q22.2 | 29988033 |
| NR1H2 | LXR-b; LXRB; NER; NER-I; RIP15; UNR | 19q13.33 | 24107776 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Liver diseases | group | 24107776 |
| Lung Neoplasms | group | 29988033 |
