1. 药材主信息
| 中文名称: | 铁丝威灵仙 |
| 英文名称: | root and rhizome of smilax |
| 拉丁名称: | Radix Smilacis |
| 使用部位: | - |
| 功用: | - |
| 适用症: | - |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 34371-14-7 | 2-Deoxy-D-ribonic-1,4-lactone | (4S,5R)-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one | 161815 |
| 389122-94-5 | (2R)-2-甲基丁酰胺 | (R)-2-Methylbutanamide | 41097729 |
| 99282-79-8 | 2-(CARBOXYMETHYL-AMINO)-4-CHLORO-BENZOIC ACID | 2-((Carboxymethyl)amino)-4-chlorobenzoic acid | 11107141 |
| 481-25-4 | - | 4-alpha-Methyl-5-alpha-cholest-7-en-3-beta-ol | 50990062 |
| 67-47-0 | 5-羟甲基糠醛 | 5-Hydroxymethylfurfural | 237332 |
| 387-80-4 | - | 5beta-Stigmastan-3beta-ol, (24S)- | 6451614 |
| 6601-66-7 | 6-去甲氧基桔皮素 | 6-Demethoxytangeretin | 629964 |
| 90921-11-2 | 白头翁素 | Anemonin | 10496 |
| 5631-70-9 | 4',5,7-三甲氧基黄酮 | Apigenin trimethyl ether | 79730 |
| 362606-60-8 | - | Clemaphenol A | 46173999 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | 7q21.12 | 27058921 |
| ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | 7q21.12 | 28958806 |
| ABCC1 | ABC29; ABCC; GS-X; MRP; MRP1 | 16p13.11 | 28958806 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 28958806 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25047426 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21198542 |
| ALDH3A1 | ALDH3; ALDHIII | 17p11.2 | 29794221 |
| AURKA | AIK; ARK1; AURA; BTAK; PPP1R47; STK15; STK6; STK7 | 20q13.2 | 25047426 |
| BAX | BCL2L4 | 19q13.33 | 25047426 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 25047426 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Body mass index | phenotype | 26249791 |
| Carcinogenesis | phenotype | 25047426 |
| Chemical and Drug Induced Liver Injury | disease | 28958806 |
| Colonic Neoplasms | group | 25047426 |
| Head and Neck Neoplasms | group | 29794221 |
| Inflammation | phenotype | 26249791 |
| Neoplasms | group | 27058921 |
| Platelet aggregation | phenotype | 24135020 |
| Thrombosis | phenotype | 24135020 |
| Xerostomia | disease | 29794221 |
