1. 药材主信息
| 中文名称: | 水飞蓟 |
| 英文名称: | Silybum Marianum |
| 拉丁名称: | - |
| 使用部位: | achene |
| 功用: | - |
| 适用症: | Acute hepatitis, chronic hepatitis, cirrhosis, fatty liver, gallstones, cholangitis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 506-30-9 | 花生酸 | - | 10467 |
| 506-30-9 | 花生酸 | - | 10467 |
| 1492-24-6 | L-2-氨基丁酸 | - | 80283 |
| 111003-33-9 | - | (-)-Taxifolin | 712316 |
| 480-41-1 | - | (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one | 667495 |
| 31721-94-5 | 5,7-二羟基色原酮 | 5,7-Dihydroxychromone | 5281343 |
| 2074-53-5 | 维生素 E | Alpha-Tocopherol | 14985 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 506-32-1 | 花生四烯酸 | Arachidonic Acid | 444899 |
| 112-85-6 | 二十二烷酸 | Behenic Acid | 8215 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| ADAMTS4 | ADAMTS-2; ADAMTS-4; ADMP-1 | 1q23.3 | 28237856 |
| ADIPOQ | ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28 | 3q27.3 | 23623334 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27710830 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Altitude Sickness | phenotype | 27105952 |
| Biliary cirrhosis | disease | 24819445 |
| Birth Weight | phenotype | 27655442 |
| Blood Pressure | phenotype | 28143892 |
| Body mass index | phenotype | 27655442 |
| Body Weight | phenotype | 23623334 |
| Carcinogenesis | phenotype | 24169354 |
| Carcinoma | group | 24169354 |
| Cholestasis | disease | 24819445 |
