1. 药材主信息
| 中文名称: | 十大功劳叶 |
| 英文名称: | leaf of leatherleaf Mahonia |
| 拉丁名称: | Folium Mahoe |
| 使用部位: | leaf |
| 功用: | - |
| 适用症: | Tuberculosis and hemoptysis, steaming bone tidal fever, dizziness and tinnitus, limp aching lumbus and knees, damp-heat jaundice, vaginal discharge, dysentery, wind-heat common cold, red eyes with gall, swollen welling abscess and sores. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 13877-91-3 | 罗勒烯 | - | 5281553 |
| 21662-16-8 | 反,反-2,4-十二碳二烯醛 | (2E,4E)-2,4-Dodecadienal | 5367530 |
| 17430-12-5 | - | (3R,6E)-nerolidol | 11241545 |
| 26137-48-4 | - | 1-Isotetrandrine | 5351212 |
| 112-12-9 | 甲基正壬酮 | 2-Undecanone | 8163 |
| 18674-16-3 | 泽泻醇A-24-醋酸酯;24-乙酰泽泻醇A; | alisol A 24-acetate | 76336194 |
| 2086-83-1 | 小檗碱 | Berberine | 2353 |
| 464-43-7 | 天然冰片（右旋龙脑） | Borneol | 6552009 |
| 41451-76-7 | - | Bruceantarin | 3084828 |
| 41451-75-6 | 鸦胆亭 | Bruceantin | 5281304 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| ANXA5 | ANX5; ENX2; HEL-S-7; PP4; RPRGL3 | 4q27 | 25682924 |
| BACH1 | BACH-1; BTBD24 | 21q21.3 | 31408727 |
| BAX | BCL2L4 | 19q13.33 | 25682924 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21496227 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 28990249 |
| CCNA1 | CT146 | 13q13.3 | 25682924 |
| CCNB1 | CCNB | 5q13.2 | 25682924 |
| CDK1 | CDC2; CDC28A; P34CDC2 | 10q21.2 | 25682924 |
| CDK4 | CMM3; PSK-J3 | 12q14.1 | 25682924 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinoma, Ovarian Epithelial | disease | 28990249 |
| Diabetes | disease | 28707095 |
| Diabetes Mellitus, Experimental | disease | 27067643 |
| Diabetes Mellitus, Experimental | disease | 20304443 |
| Endometrial Hyperplasia | disease | 28638475 |
| Glucose tolerance test | phenotype | 20304443 |
| Hyperglycemia | disease | 28707095 |
| Hyperglycemia | disease | 27067643 |
| Insulin Resistance | phenotype | 22019891 |
| Insulin Resistance | phenotype | 20304443 |
