1. 药材主信息
| 中文名称: | 生山栀 |
| 英文名称: | fruit of Cape Jasmine |
| 拉丁名称: | Fructus Gardeniae |
| 使用部位: | Gardenia jaminoides Ellis |
| 功用: | Treatment of febrile diseases with restlessness, jaundice with dark urine, hematuria with difficult painful urination, hemoptysis and epistaxis caused by heat in the blood, inflammation of the eye, boils and sores, external use for sprains and bruises.Fructus Gardeniae (charred): Hemoptysis, epistaxis, hematuria and abnormal uterine bleeding caused by heat in the blood. |
| 适用症: | 1. The active components such as crocin, crocetin, genipin, or alcoholic extract protect the liver from carbon tetrachloride and increasing biliary secretion. Oral use of its decoction induce gallbladder contraction.2. Oral or intraperitoneal use of its decoction and alcoholic extract exerts a sustained hypotensive effect in anaesthetized and un-anaesthetized animals.3. Hemostatic. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 27876-94-4 | 西红花酸；番红花酸;藏红花酸 | Crocetin | 5281232 |
| 42553-65-1 | 西红花苷I | Crocin | 5281233 |
| 6902-77-8 | 京尼平 | Genipin | 442424 |
| 529-59-9 | 染料木苷 | Genistin | 5281377 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ATG3 | APG3; APG3-LIKE; APG3L; PC3-96 | 3q13.2 | 26660048 |
| ATG5 | APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 | 6q21 | 26660048 |
| CAPN1 | CANP; CANP1; CANPL1; SPG76; muCANP; muCL | 11q13.1 | 26660048 |
| GAPDH | G3PD; GAPD; HEL-S-162eP | 12p13.31 | 28962872 |
| GAPDHP44 | GAPDH | 12q14.2 | 28962872 |
| Lamp2 | CD107b; LGP-B; Lamp II; Lamp-2; Lamp-2a; Lamp-2b; Lamp-2c; Mac3 | X A3.3|X 22.67 cM | 26660048 |
| RAB7A | CMT2B; PRO2706; RAB7 | 3q21.3 | 26660048 |
| SQSTM1 | A170; DMRV; FTDALS3; NADGP; OSIL; PDB3; ZIP3; p60; p62; p62B | 5q35.3 | 26660048 |
| UCP2 | BMIQ4; SLC25A8; UCPH | 11q13.4 | 24670857 |
| UCP2 | BMIQ4; SLC25A8; UCPH | 11q13.4 | 31384530 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinoma, Pancreatic Ductal | disease | 28962872 |
| Liver diseases | group | 26660048 |
| Myopia | disease | 31394821 |
| Pancreatic Neoplasm | disease | 28962872 |
| Sepsis | disease | 26660048 |
| Shock, Hemorrhagic | phenotype | 24670857 |
